Evidence map›Paper›PMID 37734660›Full record

ArticleAmerican journal of obstetrics & gynecology MFM2023

Early pregnancy dispositional optimism and pregnancy outcomes among nulliparous people.

Nina K Ayala, Audra C Fain, Tess E K Cersonsky, Erika F Werner, Emily S Miller, Melissa A Clark, Adam K Lewkowitz

Open access · hybridAbstract read
In one paragraph

Article in American journal of obstetrics & gynecology MFM, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Proactive Coping in Early Pregnancy and Adverse Pregnancy Outcomes.International journal of women's health · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nina K AyalaDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Women and Infants Hospital of Rhode Island, Providence, RI (Drs Ayala, Miller, and Lewkowitz); Department of Obstetrics and Gynecology, Alpert Medical School of Brown University, Providence, RI (Drs Ayala, Miller, Clark, and Lewkowitz). Electronic address: nina.ayala.md@gmail.com.
Audra C FainWarren Alpert Medical School of Brown University, Providence, RI (Drs Fain and Cersonsky).
Tess E K CersonskyWarren Alpert Medical School of Brown University, Providence, RI (Drs Fain and Cersonsky).
Erika F WernerDepartment of Obstetrics and Gynecology, Tufts University School of Medicine, Boston, MA (Dr Werner).
Emily S MillerDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Women and Infants Hospital of Rhode Island, Providence, RI (Drs Ayala, Miller, and Lewkowitz); Department of Obstetrics and Gynecology, Alpert Medical School of Brown University, Providence, RI (Drs Ayala, Miller, Clark, and Lewkowitz).
Melissa A ClarkDepartment of Obstetrics and Gynecology, Alpert Medical School of Brown University, Providence, RI (Drs Ayala, Miller, Clark, and Lewkowitz); Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI (Dr Clark).
Adam K LewkowitzDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Women and Infants Hospital of Rhode Island, Providence, RI (Drs Ayala, Miller, and Lewkowitz); Department of Obstetrics and Gynecology, Alpert Medical School of Brown University, Providence, RI (Drs Ayala, Miller, Clark, and Lewkowitz).
Brown University · USTufts University · US

Funding

Project 3: Isolating food insecurity to understand childhood health outcomes and biological mechanisms of riskP20GM139767 · NIGMS · MIRIAM HOSPITAL · PI LAURA R STROUD · 2021 to 2026
$14.6M
A novel app-based cognitive behavioral therapy intervention for preventing postpartum depressionK23HD103961 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI LEWKOWITZ, ADAM KORRICK · 2021 to 2025
$899k
NICHD NIH HHS K23 HD103961NIGMS NIH HHS P20 GM139767
6 · The paper itself

Abstract

backgroundDispositional optimism, the expectation of positive outcomes after personal challenges, is a resilience factor associated with widespread health benefits. However, the data on pregnancy-related outcomes are more limited.

objectiveThis study aimed to assess the association of early pregnancy dispositional optimism with adverse perinatal outcomes. STUDY

designThis was a prospective cohort study completed between May 2019 and February 2022 at a single, large tertiary medical center. Nulliparous pregnant people were recruited from outpatient obstetrical care sites. Participants completed a validated assessment of dispositional optimism at <20 weeks of gestation and were followed up until delivery. The primary outcome was an adverse maternal outcome composite that included gestational diabetes mellitus, hypertensive disorders of pregnancy, and/or cesarean delivery. The secondary outcomes included individual composite components and a neonatal morbidity composite. Bivariate analyses compared characteristics and primary and secondary outcomes by dispositional optimism score quartile. Multivariable logistic regression compared outcomes by dispositional optimism score quartile with the highest quartile serving as the referent, controlling for confounders determined a priori.

resultsOverall, 491 pregnant people were approached for participation, and 135 pregnant people (27.5%) declined participation. Among the 284 individuals who enrolled and had complete outcome data, the median dispositional optimism score was 16.0 (interquartile range, 14-18), and 47.9% of individuals experienced at least 1 adverse maternal outcome 135 (47.9%). After adjusting for confounders, the odds of adverse maternal outcomes were significantly higher in the lowest 2 optimism quartiles: quartile 1 (adjusted odds ratio, 3.33; 95% confidence interval, 1.57-7.36) and quartile 2 (adjusted odds ratio, 2.22; 95% confidence interval, 1.05-4.79) than the highest quartile. This was driven by significantly higher rates of hypertension (quartile 1: adjusted odds ratio, 2.62; 95% confidence interval, 1.12-6.29) and cesarean delivery (quartile 1: adjusted odds ratio, 2.75; 95% confidence interval, 1.20-6.55). There was no difference noted when quartile 3 was compared with quartile 4.

conclusionLower early pregnancy dispositional optimism was associated with significantly higher odds of adverse maternal outcomes. Interventions targeting improvements in optimism may be a novel mechanism for reducing perinatal morbidity.

Indexed as

HypertensionObstetricsCesarean SectionFemaleHumansInfant, NewbornParityPregnancyPregnancy OutcomeProspective Studiesadverse perinatal outcomescesarean deliverydispositional optimismgestational diabetes mellitushypertensive disorders of pregnancymaternal morbidityresilience

Identifiers

PMID37734660
PMCPMC10841240
OpenAlexW4386849304

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.