PERK-mediated antioxidant response is key for pathogen persistence in ticks.
Kristin L Rosche, Joanna Hurtado, Elis A Fisk, Kaylee A Vosbigian, Ashley L Warren, Lindsay C Sidak-Loftis, Sarah J Wright, Elisabeth Ramirez-Zepp, Jason M Park, Dana K Shaw
Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
Kristin L RoscheDepartment of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Joanna HurtadoDepartment of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Elis A FiskDepartment of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Kaylee A VosbigianDepartment of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Ashley L WarrenDepartment of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Lindsay C Sidak-LoftisDepartment of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Sarah J WrightDepartment of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Elisabeth Ramirez-ZeppDepartment of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.
Jason M ParkDepartment of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.ORCID 0000-0002-9050-5277
Dana K ShawDepartment of Veterinary Microbiology and Pathology, Washington State University , Pullman, Washington, USA.ORCID 0000-0002-5212-2494
Washington State University · US
Funding
TRAINING IN BIOTECHNOLOGY: EMPHASIS ON PROTEIN CHEMISTRYT32GM008336 · NIGMS · WASHINGTON STATE UNIVERSITY · PI CALL, DOUGLAS R. · 1989 to 2023
$8.9M
Infectious Diseases and Microbial Immunology Training ProgramT32AI007025 · NIAID · WASHINGTON STATE UNIVERSITY · PI Thomas H KAWULA, M KARIUKI NJENGA · 1985 to 2026
$7.4M
Tick-Pathogen Interactions: Exploring the Intersection between Stress Responses and ImmunityR01AI162819 · NIAID · WASHINGTON STATE UNIVERSITY · PI SHAW, DANA KATHLEEN · 2022 to 2025
$2.0M
Motivating Innovation and Research Achievement (MIRA)R25EB027606 · NIBIB · WASHINGTON STATE UNIVERSITY · PI Samantha Gizerian, Alla S. Kostyukova · 2020 to 2026
$1.2M
TICK-PATHOGEN INTERFACE: INVESTIGATING CROSSTALK BETWEEN STRESS RESPONSES AND IMMUNITYR21AI139772 · NIAID · WASHINGTON STATE UNIVERSITY · PI SHAW, DANA KATHLEEN · 2018 to 2019
$421k
Functional Impact of Stress Granules on Tick-Microbe InteractionsR21AI148578 · NIAID · WASHINGTON STATE UNIVERSITY · PI SHAW, DANA KATHLEEN · 2020 to 2021
A crucial phase in the life cycle of tick-borne pathogens is the time spent colonizing and persisting within the arthropod. Tick immunity is emerging as a key force shaping how transmissible pathogens interact with the vector. How pathogens remain in the tick despite immunological pressure remains unknown. In persistently infected
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
PERK-mediated antioxidant response is key for pathogen persistence in ticks. · full record | OpenQuestion