Evidence map›Paper›PMID 37733160›Full record

ReviewClinical autonomic research : official journal of the Clinical Autonomic Research Society2023

Assessment of comorbid symptoms in pediatric autonomic dysfunction.

Sally E Tarbell, Erin L Olufs, Philip R Fischer, Gisela Chelimsky, Mohammed T Numan, Marvin Medow, Hasan Abdallah, Shelley Ahrens, Jeffrey R Boris, Ian J Butler and 15 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Reduced gut microbial diversity characterized by decreasedFrontiers in cellular and infection microbiology · 2026
    Observational
  3. Observational
  4. How should we measure the "POT" of POTS, and how much does it matter?Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Article
  5. Comment to the article "Standing tests lack reliability to diagnose all adolescents who have postural tachycardia syndrome".Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 13 institutions in 3 countries.

Sally E TarbellNorthwestern University Feinberg School of Medicine, Chicago, IL, USA. Sally.Tarbell@northwestern.edu.ORCID 0000-0003-3661-0161
Erin L OlufsIowa Stead Family Children's Hospital, Iowa City, IA, USA.
Philip R FischerMayo Clinic, Rochester, MN, USA.
Gisela ChelimskyChildren's Hospital of Richmond, Richmond, VA, USA.
Mohammed T NumanUniversity of Texas McGovern Medical School, Houston, TX, USA.
Marvin MedowNew York Medical College, Valhalla, NY, USA.
Hasan AbdallahChildren's Heart Institute, Herndon, VA, USA.
Shelley AhrensMayo Clinic, Rochester, MN, USA.
Jeffrey R BorisJeffrey R. Boris, MD LLC, Moylan, PA, USA.
Ian J ButlerUniversity of Texas McGovern Medical School, Houston, TX, USA.
Thomas C ChelimskyVirginia Commonwealth University Health, Richmond, VA, USA.
Craig ColebyGranger Medical Clinic, Riverton, UT, USA.
John E FortunatoNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Raewyn GavinStarship Children's Hospital, Auckland, New Zealand.
Janice GildenRosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Renato GonikUniversity of Florida College of Medicine, Gainesville, FL, USA.
Kelsey KlaasMayo Clinic, Rochester, MN, USA.
Lauren MarsillioNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Erin MarriottAmerican Family Children's Hospital, Madison, WI, USA.
Laura A PaceMetrodora Institute, Salt Lake City, UT, USA.
Paul PianosiUniversity of Minnesota Medical School, Minneapolis, MN, USA.
Pippa SimpsonMedical College of Wisconsin, Milwaukee, WI, USA.
Julian StewartNew York Medical College, Valhalla, NY, USA.
Natalie Van WaningIowa Stead Family Children's Hospital, Iowa City, IA, USA.
Debra E Weese-MayerNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Northwestern University · USMayo Clinic in Arizona · USNew York Medical College · USThe University of Texas Health Science Center at Houston · USUniversity of Iowa Stead Family Children’s Hospital · USVirginia Commonwealth University · USKhalifa University of Science and Technology · AEMedical College of Wisconsin · USRosalind Franklin University of Medicine and Science · USStarship Children's Health · NZUniversity of Florida · USUniversity of Minnesota Medical Center · USUniversity of Wisconsin American Family Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePediatric patients with autonomic dysfunction and orthostatic intolerance (OI) often present with co-existing symptoms and signs that might or might not directly relate to the autonomic nervous system. Our objective was to identify validated screening instruments to characterize these comorbidities and their impact on youth functioning.

methodsThe Pediatric Assembly of the American Autonomic Society reviewed the current state of practice for identifying symptom comorbidities in youth with OI. The assembly includes physicians, physician-scientists, scientists, advanced practice providers, psychologists, and a statistician with expertise in pediatric disorders of OI. A total of 26 representatives from the various specialties engaged in iterative meetings to: (1) identify and then develop consensus on the symptoms to be assessed, (2) establish committees to review the literature for screening measures by member expertise, and (3) delineate the specific criteria for systematically evaluating the measures and for making measure recommendations by symptom domains.

resultsWe review the measures evaluated and recommend one measure per system/concern so that assessment results from unrelated clinical centers are comparable. We have created a repository to apprise investigators of validated, vetted assessment tools to enhance comparisons across cohorts of youth with autonomic dysfunction and OI.

conclusionThis effort can facilitate collaboration among clinical settings to advance the science and clinical treatment of these youth. This effort is essential to improving management of these vulnerable patients as well as to comparing research findings from different centers.

Indexed as

Autonomic Nervous System DiseasesOrthostatic IntoleranceAdolescentAutonomic Nervous SystemChildHumansAssessment measuresAutonomic dysfunctionComorbiditiesOrthostatic intolerancePediatric

Identifiers

PMID37733160
OpenAlexW4386910641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.