Evidence map›Paper›PMID 37732549›Full record

ArticleMolecular medicine reports2023

Britanin inhibits titanium wear particle‑induced osteolysis and osteoclastogenesis.

Ju Ang Kim, Soomin Lim, Hye Jung Ihn, Jung-Eun Kim, Kyungmoo Yea, Jimin Moon, Hyukjae Choi, Eui Kyun Park

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Clusterzymes-driven therapy: ultrasmall CuJournal of nanobiotechnology · 2026
    Article
  3. Britanin - a beacon of hope against gastrointestinal tumors?World journal of clinical oncology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ju Ang Kim *Department of Oral Pathology and Regenerative Medicine, School of Dentistry, Institute for Hard Tissue and Bio‑tooth Regeneration, Kyungpook National University, Daegu 41940, Republic of Korea.
Soomin Lim *Department of Oral Pathology and Regenerative Medicine, School of Dentistry, Institute for Hard Tissue and Bio‑tooth Regeneration, Kyungpook National University, Daegu 41940, Republic of Korea.
Hye Jung IhnCell and Matrix Research Institute, Kyungpook National University, Daegu 41944, Republic of Korea.
Jung-Eun KimDepartment of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea.
Kyungmoo YeaDepartment of New Biology, Daegu Gyeongbuk Institute of Science and Technology, Daegu 42988, Republic of Korea.
Jimin MoonCollege of Pharmacy, Research Institution of Cell Culture, Yeungnam University, Gyeongsan, Gyeongbuk 38541, Republic of Korea.
Hyukjae ChoiCollege of Pharmacy, Research Institution of Cell Culture, Yeungnam University, Gyeongsan, Gyeongbuk 38541, Republic of Korea.
Eui Kyun ParkDepartment of Oral Pathology and Regenerative Medicine, School of Dentistry, Institute for Hard Tissue and Bio‑tooth Regeneration, Kyungpook National University, Daegu 41940, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wear particle‑induced osteolysis is a serious complication that occurs in individuals with titanium (Ti)‑based implants following long‑term usage due to loosening of the implants. The control of excessive osteoclast differentiation and inflammation is essential for protecting against wear particle‑induced osteolysis. The present study evaluated the effect of britanin, a pseudoguaianolide sesquiterpene isolated from

Indexed as

OsteogenesisOsteolysisActin CytoskeletonAnimalsDisease Models, AnimalHumansMiceOsteoclastsTitaniumTitaniumB lymphocyte-induced maturation protein-1britanincytoplasmic 1nuclear factor of activated T-cellsosteoclastosteolysistitanium particles

Identifiers

PMID37732549
PMCPMC10539997

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.