Evidence map›Paper›PMID 37732251›Full record

ArticlebioRxiv : the preprint server for biology2023

Drugs of abuse hijack a mesolimbic pathway that processes homeostatic need.

Bowen Tan, Caleb J Browne, Tobias Nöbauer, Alipasha Vaziri, Jeffrey M Friedman, Eric J Nestler

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Bowen TanLaboratory of Molecular Genetics, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA.
Caleb J BrowneNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Tobias NöbauerLaboratory of Neurotechnology and Biophysics, The Rockefeller University, New York, NY 10065, USA.
Alipasha VaziriLaboratory of Neurotechnology and Biophysics, The Rockefeller University, New York, NY 10065, USA.
Jeffrey M FriedmanLaboratory of Molecular Genetics, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA.
Eric J NestlerNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Allen Institute for Brain Science · USHoward Hughes Medical Institute · USRockefeller University · US

Funding

Transcription Factors in Stimulant and Opioid ActionP01DA047233 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI YASMIN L. HURD · 2019 to 2026
$16.5M
Neurotrophic Mechanisms in Opiate and Cocaine ActionR01DA014133 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI ERIC J. NESTLER · 2000 to 2026
$12.1M
Optimization, application and dissemination of high-speed hybrid multiphoton volumetric imaging technologiesU01NS115530 · NINDS · ROCKEFELLER UNIVERSITY · PI LOSONCZY, ATTILA, VAZIRI, ALIPASHA · 2020 to 2023
$4.7M
Lensless, high-speed and multi-region volumetric Ca2+ imaging of up to 1cm2 brain surface across model animalsRF1NS110501 · NINDS · ROCKEFELLER UNIVERSITY · PI ROBINSON, JACOB T., VAZIRI, ALIPASHA · 2019 to 2019
$2.8M
In vivo Imaging of Neuroactivity in the Deep Forward Scattering Regime Using Speckle Identification and Demixing (SPID) MicroscopyRF1NS113251 · NINDS · ROCKEFELLER UNIVERSITY · PI GIGAN, SYLVAIN, VAZIRI, ALIPASHA · 2019 to 2019
$2.1M
NIDA NIH HHS P01 DA047233NIDA NIH HHS R01 DA014133NINDS NIH HHS RF1 NS110501NINDS NIH HHS RF1 NS113251NINDS NIH HHS U01 NS115530
6 · The paper itself

Abstract

Addiction prioritizes drug use over innate needs by "hijacking" brain circuits that direct motivation, but how this develops remains unclear. Using whole-brain FOS mapping and

Identifiers

PMID37732251
PMCPMC10508763
OpenAlexW4386446133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.