Evidence map›Paper›PMID 37732236›Full record

ArticlebioRxiv : the preprint server for biology2023

Evaluation of

Yu-Peng Zhou, Marc D Normandin, Vasily Belov, Marina T Macdonald-Soccorso, Sung-Hyun Moon, Yang Sun, Georges El Fakhri, Nicolas J Guehl, Pedro Brugarolas

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yu-Peng ZhouGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Marc D NormandinGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Vasily BelovGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Marina T Macdonald-SoccorsoGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Sung-Hyun MoonGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Yang SunGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Georges El FakhriGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Nicolas J GuehlGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Pedro BrugarolasGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Harvard University · US

Funding

Unified Joint Statistical Reconstruction of PET & MRP41EB022544 · NIBIB · YALE UNIVERSITY · PI Marc David Normandin · 2017 to 2026
$14.8M
Development of a PET radioligand for alpha2delta-1 receptors to visualize and quantify neuropathic pain mechanisms neuropathic pain mechanismsR21NS120139 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI BRUGAROLAS, PEDRO · 2020 to 2020
$456k
Development of next generation of α2δ-1 PET tracers for neuroimagingK99EB033407 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ZHOU, YU-PENG · 2022 to 2023
$182k
Gamma counter and continuous blood sampler for quantitative PET imagingS10OD018035 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES, NORMANDIN, MARC DAVID · 2014 to 2014
$144k
NIBIB NIH HHS K99 EB033407NIBIB NIH HHS P41 EB022544NIH HHS S10 OD018035NINDS NIH HHS R21 NS120139
6 · The paper itself

Abstract

Gabapentin, a selective ligand for the α2δ subunit of voltage-dependent calcium channels, is an anticonvulsant medication used in the treatment of neuropathic pain, epilepsy and other neurological conditions. We recently described two radiofluorinated derivatives of gabapentin (

Indexed as

brain imagingfluorine-18gabapentinPETRadiotracervoltage-dependent calcium channelsα2δ

Identifiers

PMID37732236
PMCPMC10508714
OpenAlexW4386448501

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.