Evidence map›Paper›PMID 37732180›Full record

ArticlebioRxiv : the preprint server for biology2023

Loss of ATP-sensitive channel expression and function decreases opioid sensitivity in a mouse model of type 2 diabetes.

Cole Fisher, Kayla Johnson, Madelyn Moore, Amir Sadrati, Jody L Janecek, Melanie L Graham, Amanda H Klein

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cole FisherDepartment of Pharmacy Practice and Pharmaceutical Sciences, University of Minnesota, Duluth, MN, USA.
Kayla JohnsonDepartment of Pharmacy Practice and Pharmaceutical Sciences, University of Minnesota, Duluth, MN, USA.
Madelyn MooreDepartment of Pharmacy Practice and Pharmaceutical Sciences, University of Minnesota, Duluth, MN, USA.
Amir SadratiDepartment of Pharmacy Practice and Pharmaceutical Sciences, University of Minnesota, Duluth, MN, USA.
Jody L JanecekDepartment of Surgery, University of Minnesota, St. Paul, MN, USA.
Melanie L GrahamDepartment of Surgery, University of Minnesota, St. Paul, MN, USA.
Amanda H KleinDepartment of Pharmacy Practice and Pharmaceutical Sciences, University of Minnesota, Duluth, MN, USA.
University of Minnesota · US

Funding

KATP Channels as Downstream targets of adenylyl cyclases during opioid tolerance and withdrawalR01DA051876 · NIDA · UNIVERSITY OF MINNESOTA · PI KLEIN, AMANDA HELEN · 2021 to 2025
$2.9M
NIDA NIH HHS R01 DA051876
6 · The paper itself

Abstract

During diabetes, β-cell dysfunction due to loss of potassium channels sensitive to ATP, known as K

Indexed as

ATP-gated potassium channelsneuropathynociceptionopioidsulfonylurea

Identifiers

PMID37732180
PMCPMC10508758
OpenAlexW4386468464

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.