ArticleFrontiers in public health2023
The impact of comorbidities on tuberculosis treatment outcomes in Poland: a national cohort study.
Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- A Comparative Policy Review of Tuberculosis Infection Control Policies Across Six Countries: Insights on Screening, Prevention, and Treatment Strategies.Health science reports · 2026Article
- Risk factors for treatment failure of drug-resistant pulmonary tuberculosis: results from a two-decade data analysis.Journal of thoracic disease · 2026Article
- Cohort evaluation of an all-oral shorter regimen for drug-resistant tuberculosis in Ecuador.BMC infectious diseases · 2026Article
- Impact of comorbid diseases and associated factors on tuberculosis treatment outcomes among tuberculosis patients in South West Oromia, Ethiopia: a retrospective cohort study.Scientific reports · 2026Article
- Complex Disseminated Tuberculosis with Oral and Gastrointestinal Involvement: Histopathologic and Clinical Insights.Diagnostics (Basel, Switzerland) · 2026Article
- Treatment outcomes among tuberculosis patients with co-morbidities at Ghana's premier national referral centre: a retrospective cross-sectional study.BMC infectious diseases · 2026Article
- Article
- Survival Analysis of Risk Factors for Death in Patients With TB Based on Clinical and Imaging Characteristics.Canadian respiratory journal · 2026Article
- Methodologies for studying depression in persons with tuberculosis: A scoping review.PLOS global public health · 2026Article
- Cox Proportional Hazards Model Analysis of Survival Among Tuberculosis Patients Under Treatment in Mbuji-Mayi, Democratic Republic of the Congo.Journal of multidisciplinary healthcare · 2026Article
- Risk Factors for Treatment Failure of Drug-Susceptible Pulmonary Tuberculosis in Lithuania over 22 Years.Medicina (Kaunas, Lithuania) · 2025Article
- Drug Resistance and Comorbidities in the Treatment of Pulmonary Tuberculosis: A Multicenter Retrospective Cohort Study.Antibiotics (Basel, Switzerland) · 2025Article
- Tuberculosis treatment failure: what are the risk factors? A comprehensive literature review.Multidisciplinary respiratory medicine · 2025Article
- Uncovering the burden of tuberculosis in Algeria: a retrospective analysis from 2019 to 2024.Antonie van Leeuwenhoek · 2025Article
- Knowledge and Prevalence of Latent Tuberculosis Infection: A Feasibility and Pilot Study in a Primary Healthcare Setting in Rural Eastern Cape, South Africa.International journal of environmental research and public health · 2025Article
- Assessment of comorbidities, risk factors, and post tuberculosis lung disease in National Tuberculosis Guidelines: A scoping review.PLOS global public health · 2025Article
- Comorbidities, drug-resistance and length of hospital stay among tuberculosis inpatients in Northeastern China: a retrospective observational study from 2013 to 2021.BMC infectious diseases · 2024Observational
- Tuberculosis treatment outcomes and associated factors: A retrospective study in West Nusa Tenggara, Indonesia.Narra J · 2024Article
- Non-communicable comorbidities in pulmonary tuberculosis and healthcare utilization: a cross-sectional study of 2021 Indonesian national health insurance data.Archives of public health = Archives belges de sante publique · 2024Article
- Article
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3 authors.
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Abstract
Background: Tuberculosis (TB) is a complex disease associated with other medical conditions, that may affect disease severity. This study aimed to investigate the impact of comorbidities on treatment outcomes and mortality rates in patients with TB in Poland. Methods: We analyzed a national cohort of 19,217 adult TB patients diagnosed between 2011 and 2016 in Poland. We compared treatment success rates and mortality rates in patients with comorbidities and those without to assess the impact of various comorbidities on these outcomes. Odds ratios (OR) were calculated to quantify the association between comorbidities and TB treatment outcomes. Results: Patients with comorbidities had lower treatment success rates and higher mortality rates. Diabetes was identified as a significant risk factor for increased TB mortality (OR = 1.9) and mortality from all other causes (OR = 4.5). Similar associations were found for alcoholism (OR = 8.3 and OR = 7.1), immunosuppressive therapy (OR = 5.7 and OR = 5.9), and cancer (OR = 3.4 and OR = 15.4). HIV and tobacco use were associated with an increased risk of mortality from causes other than TB, with odds ratios of 28.6 and 2.2, respectively. The overall treatment success rate in the study population was 88.0%, with 9.2% of patients failing to achieve treatment success and 2.8% dying. Comorbidities such as diabetes, alcoholism, substance addiction, immunosuppressive therapy, cancer, and tobacco use increased the risk of tuberculosis treatment failure. Conclusion: Patients with comorbidities face a higher risk of unsuccessful treatment outcomes and increased mortality. It is essential to implement integrated management strategies that address both TB and comorbid conditions to improve treatment success rates and reduce mortality.
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