Evidence map›Paper›PMID 37732076›Full record

ArticleFrontiers in psychiatry2023

Racial differences in pathways to care preceding first episode mania or psychosis: a historical cohort prodromal study.

Manuel Gardea-Resendez, Javier Ortiz-Orendain, Alessandro Miola, Manuel Fuentes Salgado, Mete Ercis, Brandon J Coombes, Peggy M Gruhlke, J Michael Bostwick, Ian Michel, Jennifer L Vande Voort and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Manuel Gardea-ResendezDepartment of Psychiatry, Universidad Autónoma de Nuevo León, Monterrey, Mexico.
Javier Ortiz-OrendainDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.
Alessandro MiolaDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.
Manuel Fuentes SalgadoDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.
Mete ErcisDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.
Brandon J CoombesDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.
Peggy M GruhlkeDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.
J Michael BostwickDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.
Ian MichelMayo Clinic Alix School of Medicine, Mayo Clinic, Rochester, MN, United States.
Jennifer L Vande VoortDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.
Aysegul OzerdemDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.
Alastair McKeanDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.
Mark A FryeDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.
Monica Taylor-DesirDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.
Mayo Clinic · USWinnMed · USMayo Clinic in Arizona · USMayo Clinic in Florida · US

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
NIA NIH HHS R01 AG034676NIA NIH HHS R33 AG058738
6 · The paper itself

Abstract

Background: There is evidence suggesting racial disparities in diagnosis and treatment in bipolar disorder (BD) and schizophrenia (SZ). The purpose of this study is to compare psychiatric diagnoses and psychotropic use preceding a first episode of mania (FEM) or psychosis (FEP) in racially diverse patients. Methods: Using a comprehensive medical records linkage system (Rochester Epidemiology Project, REP), we retrospectively identified individuals diagnosed with BD or SZ and a documented first episode of mania or psychosis. Illness trajectory before FEP/FEM were characterized as the time from first visit for a mental health complaint to incident case. Pathways to care and clinical events preceding FEP/FEM were compared based on subsequent incident case diagnosis (BD or SZ) and self-reported race (White vs. non-White). Results: A total of 205 (FEM = 74; FEP = 131) incident cases were identified in the REP. Duration of psychiatric antecedents was significantly shorter in non-White patients, compared to White patients (2.2 ± 4.3 vs. 7.4 ± 6.6 years; Conclusion: These data are unable to ascertain reasons for shorter duration of psychiatric antecedents and later age of seeking care, and more broadly first age of initial symptom presentation. If symptoms are confirmed to be earlier than first time seeking care in both groups, it would be important to identify barriers that racial minorities face to access timely psychiatric care and optimize early intervention strategies.

Indexed as

bipolar disorderfirst episode maniafirst episode psychosisprodromeschizophrenia

Identifiers

PMID37732076
PMCPMC10507622
OpenAlexW4386423040

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.