Evidence map›Paper›PMID 37731820›Full record

ArticleFrontiers in cellular and infection microbiology2023

Experimental and

Javaria Saeed, Syed Nisar Hussain Shah, Hina Javed, Asma Aslam, Anam Ali, Farhan Siddique, Tahreem Zahra, Yousef A Bin Jardan, Gezahign Fentahun Wondmie, Hiba-Allah Nafidi and 1 more

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Javaria SaeedDepartment of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan.
Syed Nisar Hussain ShahDepartment of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan.
Hina JavedDepartment of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan.
Asma AslamDepartment of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan.
Anam AliDepartment of Pharmacology, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan.
Farhan SiddiqueDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan.
Tahreem ZahraInstitute of Zoology, Bahauddin Zakariya University, Multan, Pakistan.
Yousef A Bin JardanDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Gezahign Fentahun WondmieDepartment of Biology, Bahir Dar University, Bahir Dar, Ethiopia.
Hiba-Allah NafidiDepartment of Food Science, Faculty of Agricultural and Food Sciences, Laval University, Quebec City, QC, Canada.
Mohammed BourhiaDepartment of Chemistry and Biochemistry, Faculty of Medicine and Pharmacy, Ibn Zohr University, Laayoune, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The current study aimed to develop a topical herbal emulgel containing Method: The CT emulgel was formulated by response surface methodology (RSM) and was evaluated by various parameters like extrudability, spreadability, pH, viscosity, and antibacterial and antioxidant activities. Molecular docking was also performed using AutoDock. Results: Among all formulated CT emulgels, F9 and F8 were optimized. Optimized formulations had shown good spreadability and extrudability characteristics. Sample F8 had % inhibition of 42.131 ± 0.335, 56.720 ± 0.222, and 72.440 ± 0.335 at different concentrations. Sample F9 had % inhibition of 26.312 ± 0.280, 32.461 ± 0.328, and 42.762 ± 0.398 at concentrations of 250 µg/ml, 500 µg/ml, and 1,000 µg/ml, respectively, which shows that both samples F8 and F9 have significant antioxidant potential. Optimized CT emulgels F8 and F9 had significant antibacterial activity against Conclusion: The current study suggests that

Indexed as

Carthamus tinctoriusSkin Diseases, BacterialAnti-Bacterial AgentsAntioxidantsEscherichia coliMolecular Docking SimulationPlant ExtractsStaphylococcus aureusAnti-Bacterial AgentsAntioxidantsPlant Extractsanti-bacterialanti-oxidant activityCarthamus tinctorius L oilextractionmolecular docking

Identifiers

PMID37731820
PMCPMC10508954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.