Evidence map›Paper›PMID 37731243›Full record

ArticleBiophysical journal2023

Crystal structures of human serum albumin in complex with lysophosphatidylcholine.

Yu Wang, Zhipu Luo, Xavier Morelli, Peng Xu, Longguang Jiang, Xiaoli Shi, Mingdong Huang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Yu WangCollege of Chemistry, Fuzhou University, Fuzhou, China; Key Laboratory of Pathogenic Fungi and Mycotoxins of Fujian Province, School of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Zhipu LuoSoochow University, Suzhou, China.
Xavier MorelliCRCM, CNRS, INSERM, Institut Paoli-Calmettes, University Aix-Marseill1715e, Marseille, France.
Peng XuCollege of Biological Science and Engineering, Fuzhou University, Fuzhou, China.
Longguang JiangCollege of Chemistry, Fuzhou University, Fuzhou, China. Electronic address: jianglg@fzu.edu.cn.
Xiaoli ShiState Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian, China. Electronic address: sxl_sharly@fjirsm.ac.cn.
Mingdong HuangCollege of Chemistry, Fuzhou University, Fuzhou, China. Electronic address: hmd_lab@fzu.edu.cn.
Fuzhou University · CNCentre National de la Recherche Scientifique · FRChinese Academy of Sciences · CNFujian Agriculture and Forestry University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lysophospholipids (lysoPLs) are crucial metabolites involved in various physiological and pathological cellular processes. Understanding their binding interactions, particularly with human serum albumin (HSA), is essential due to their role in regulating lysoPLs-induced cytotoxicity. However, the precise mechanism of lysoPLs binding to HSA remains elusive. In this study, we employed fluorescence quenching and optical interferometry assays to demonstrate direct binding between lysophosphatidylcholine (LPC) and HSA (K

Indexed as

LysophosphatidylcholinesSerum Albumin, HumanFatty AcidsHumansModels, MolecularMyristatesProtein BindingSerum AlbuminFatty AcidsLysophosphatidylcholinesMyristatesSerum AlbuminSerum Albumin, Human

Identifiers

PMID37731243
PMCPMC10645546
OpenAlexW4386861264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.