Evidence map›Paper›PMID 37731066›Full record

ArticleLangenbeck's archives of surgery2023

Assessment of the level III of Inoue by preoperative endoscopic ultrasound and elastography: a novel approach to predict a periarterial divestment technique in borderline resectable (BR) or locally advanced (LA) pancreatic adenocarcinoma-How I do it.

Piero Alberti, Elizabeth Pando, Monder Abu-Suboh, Miquel Masachs, Xavier Merino, Maite Salcedo, Teresa Macarulla, Joaquin Balsells, Ramon Charco

Open access · hybridAbstract read
In one paragraph

Article in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Piero AlbertiDepartment of Surgery, Universitat Autonoma de Barcelona, Barcelona, Spain.
Elizabeth PandoDepartment of Surgery, Universitat Autonoma de Barcelona, Barcelona, Spain. elizabeth.pando@vallhebron.cat.ORCID http://orcid.org/0000-0001-6898-5502
Monder Abu-SubohDigestive Endoscopy Unit, Hospital Vall d'Hebron, Barcelona, Spain.
Miquel MasachsDigestive Endoscopy Unit, Hospital Vall d'Hebron, Barcelona, Spain.
Xavier MerinoRadiology Department, Hospital Vall d'Hebron, Barcelona, Spain.
Maite SalcedoAnatomopathology Department, Hospital Vall d'Hebron, Barcelona, Spain.
Teresa MacarullaOncology Department, Hospital Vall d'Hebron, Vall d´Hebrón Institute of Oncology, Barcelona, Spain.
Joaquin BalsellsDepartment of Hepatopancreatobiliary and Trasplant Surgery, Hospital Vall d'Hebron, Barcelona, Spain.
Ramon CharcoDepartment of Hepatopancreatobiliary and Trasplant Surgery, Hospital Vall d'Hebron, Barcelona, Spain.
Vall d'Hebron Hospital Universitari · ESUniversitat Autònoma de Barcelona · ESHebron University · PS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeriarterial divestment is a surgical technique to approach borderline resectable (BR) or locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC) with arterial involvement. There are no reports in the literature regarding the role of endoscopic ultrasound and elastography (EUS-EG) in exploring the integrity of Inoue's level III and its correlation with the periarterial divestment technique feasibility. Our research is aimed at exploring the role of EUS-EG in this scenario.

methodsWe describe our approach to Inoue's level II by EUS-EG in patients with BR and LA pancreatic cancer patients after neoadjuvant chemotherapy.

resultsBetween June 2019 and December 2020, four patients out of 25 were eligible to perform a preoperative EUS-EG. In all cases, Inoue's level III integrity was corroborated by EUS-EG and confirmed posteriorly in the surgical scenario where a periarterial divestment technique was feasible. Vein resections were necessary in all cases, with no need for arterial resection. An R0 (> 1 mm) margin was achieved in all patients, and the histopathological assessment showed the presence of neurovascular tissue at the peripheral arterial margin.

conclusionPreoperatively, EUS-EG is a novel approach to explore the integrity of Inoue's level III and could be helpful to preclude a periarterial divestment technique in borderline resectable or locally advanced pancreatic adenocarcinoma with arterial involvement.

Indexed as

AdenocarcinomaElasticity Imaging TechniquesNeoplasms, Second PrimaryPancreatic NeoplasmsEndosonographyHumansBorderline pancreatic cancerLocally advanced pancreatic cancerPancreatic cancerPeriarterial divestmentTriangle operation

Identifiers

PMID37731066
PMCPMC10511378
OpenAlexW4386880196

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.