ArticleScientific reports2023
Statistical optimization, characterization, antioxidant and antibacterial properties of silver nanoparticle biosynthesized by saw palmetto seed phenolic extract.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 26 citations in OpenAlex.
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- Molecular interaction and synergistic effects of silver nanoparticles capped by thesinic acid in sodium alginate films: Toward active preservation and intelligent freshness monitoring.Food chemistry: X · 2026Article
- Biosynthesis of silver nanoparticles using Musca domestica extract as a novel bioresource for therapeutic evaluation.Discover nano · 2026Article
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- Synergistic enzyme action boosts phenolic compounds in flaxseed during germination using a two-level factorial design.Scientific reports · 2025Article
- Recent Advances of Silver Nanoparticles in Wound Healing: Evaluation of In Vivo and In Vitro Studies.International journal of molecular sciences · 2025Review
- Structural peculiarities of the silver-containing nanocomposites based on carboxymethyl cellulose-chitosan polyelectrolyte complexes and their antimicrobial and antiviral applications.Scientific reports · 2025Article
- Comparison of anti-biofilm and cytotoxic activity of Ag/AgO, Ag/AgScientific reports · 2025Article
- Phytosynthesis and Characterization of Silver Nanoparticles fromPharmaceutics · 2025Article
- Upcycling defatted rice bran into alginate based noodles via hydrocolloid assisted development and assessment of structural and functional properties.Current research in food science · 2025Article
- Perspectives and Possibilities for New Antimicrobial Agents in the Treatment and Control ofInternational journal of molecular sciences · 2024Review
- Green-Synthesized Characterization, Antioxidant and Antibacterial Applications of CtAC/MNPs-Ag Nanocomposites.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Monocyte (THP-1) Response to Silver Nanoparticles Synthesized withNanomaterials (Basel, Switzerland) · 2024Article
- Sustainable synthesis of silver nanoparticles fromFrontiers in chemistry · 2024Article
- Biosynthesis, characterization, and antifungal activity of plant-mediated silver nanoparticles usingFrontiers in microbiology · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
On the global market, silver nanoparticles (Ag-NPs) are in high demand for their various applications in biomedicine, material engineering, and consumer products. This study highlighted the biosynthesis of the Ag-NPs using saw palmetto seed phenolic extract (SPS-phenolic extract), which contained vital antioxidant-phenolic compounds. Herein, central composite statistical design, response surface methodology, and sixteen runs were conducted to optimize Ag-NPs biosynthesis conditions for maximizing the production of Ag-NPs and their phenolic content. The best-produced SPS-Ag-NPs showed a surface plasmon resonance peak at 460 nm and nano-spherical sizes ranging from 11.17 to 38.32 nm using the UV spectrum analysis and TEM images, respectively. The produced SPS-Ag-NPs displayed a high negative zeta-potential value (- 32.8 mV) demonstrating their high stability. The FTIR analysis demonstrated that SPS-phenolic compounds were involved in sliver bio-reduction and in stabilizing, capping, and preventing Ag-NP aggregation. The thermogravimetric investigation revealed that the produced SPS-Ag-NPs have remarkable thermal stability. The produced SPS-Ag-NP exceeded total antioxidant activity (13.8 µmol Trolox equivalent) more than the SPS-phenolic extract (12.0 µmol Trolox equivalent). The biosynthesized SPS-Ag-NPs exhibited noticeably better antibacterial activity against multidrug-resistant Gram-negative E. coli and Gram-positive S. aureus compared to SPS-phenolic extract. Hence, the bio-synthesized SPS-Ag-NPs demonstrated great potential for use in biomedical and antimicrobial applications.
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