Evidence map›Paper›PMID 37730946›Full record

ArticleJournal of assisted reproduction and genetics2023

Clinicians' perspectives on barriers and facilitators to sperm banking in adolescent males with cancer: a mixed-methods study.

Leena Nahata, Sophia M Liles, Cynthia A Gerhardt, Ashley J Housten, Dona Jalili, Sarah H O'Brien, Susan T Vadaparampil, Gwendolyn P Quinn

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of assisted reproduction and genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Leena NahataThe Abigail Wexner Research Institute at Nationwide Children's Hospital, 431 S 18th St, Columbus, OH, 43205, USA. leena.nahata@nationwidechildrens.org.ORCID http://orcid.org/0000-0003-3899-2642
Sophia M LilesThe Abigail Wexner Research Institute at Nationwide Children's Hospital, 431 S 18th St, Columbus, OH, 43205, USA.ORCID https://orcid.org/0000-0003-2883-9695
Cynthia A GerhardtThe Abigail Wexner Research Institute at Nationwide Children's Hospital, 431 S 18th St, Columbus, OH, 43205, USA.ORCID https://orcid.org/0000-0002-4376-3652
Ashley J HoustenDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.ORCID https://orcid.org/0000-0002-7379-0678
Dona JaliliDepartment of Obstetrics and Gynecology, NYU School of Medicine, New York, NY, USA.ORCID https://orcid.org/0009-0003-1991-0397
Sarah H O'BrienThe Abigail Wexner Research Institute at Nationwide Children's Hospital, 431 S 18th St, Columbus, OH, 43205, USA.ORCID https://orcid.org/0000-0001-8855-9746
Susan T VadaparampilDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.ORCID https://orcid.org/0000-0002-1052-6917
Gwendolyn P QuinnDepartment of Obstetrics and Gynecology, NYU School of Medicine, New York, NY, USA.ORCID https://orcid.org/0000-0002-4208-9889
Nationwide Children's Hospital · USNew York University · USMoffitt Cancer Center · USWashington University in St. Louis · US

Funding

LOvE (LGBT Oncofertility Education) ECHOR25CA142519 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Gwendolyn P Quinn, SUSAN T VADAPARAMPIL · 2011 to 2026
$4.0M
Optimizing fertility preservation and decision quality in male AYA with cancer: A family-centered interventionK08CA237338 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI NAHATA, LEENA · 2019 to 2023
$1.0M
NCI NIH HHS K08 CA237338NCI NIH HHS K08CA237338NCI NIH HHS R25 CA142519
6 · The paper itself

Abstract

purposeTo examine processes, barriers, and facilitators to sperm banking counseling and decision-making for adolescent males newly diagnosed with cancer from the perspective of clinicians who completed Oncofertility communication training. We also identify opportunities for improvement to inform future interventions and implementation.

methodsA survey (N=104) and subsequent focus groups (N=15) were conducted with non-physician clinicians practicing in pediatric oncology who completed Oncofertility communication training.

resultsMost survey participants were confident in communicating about the impact of cancer on fertility (n=87, 83.7%) and fertility preservation options (n=80, 76.9%). Most participants reported never/rarely using a sperm banking decision tool (n=70, 67.3%), although 98.1% (n=102) said a decision tool with a family-centered approach would be beneficial. Primary themes in the subsequent focus groups included variable processes/workflows (inconsistent approaches to consult initiation; involvement of adolescents, caregivers, and various clinician types; assessment of puberty/sexual experience), structural and psychosocial barriers (cost and logistics, developmental, cultural, clinical acuity/prognosis), and facilitators (educational materials, alternative options for banking). Opportunities and strategies for improvement (including fertility preservation in existing research protocols; additional staffing/resources; oncologist education and buy-in; and development of decision tools) were informed by challenges identified in the other themes.

conclusionBarriers to adolescent sperm banking remain, even among clinicians who have completed Oncofertility training. Although training is one factor necessary to facilitate banking, structural and psychosocial barriers persist. Given the complexities of offering sperm banking to pediatric populations, continued efforts are needed to mitigate structural barriers and develop strategies to facilitate decision-making before childhood cancer treatment.

Indexed as

Fertility PreservationNeoplasmsAdolescentChildCounselingHumansMaleSemenSpermatozoaCliniciansDecision-makingFertility counselingFertility preservationOncofertility

Identifiers

PMID37730946
PMCPMC10656382
OpenAlexW4386909841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.