Evidence map›Paper›PMID 37730920›Full record

ArticleAnalytical and bioanalytical chemistry2023

Target immobilization on glass microfiber membranes as a label-free strategy for hit identification.

Yinan Wang, Yan He, Xiaojiao Ye, Yixiao Zhang, Xiuxiu Huang, Hongli Liu, Wenqing Dong, Dongzhi Yang, Dong Guo

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 71% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yinan Wang *Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Yan He *Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Xiaojiao YeJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Yixiao ZhangJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Xiuxiu HuangJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Hongli LiuJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Wenqing DongJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Dongzhi YangJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China. dongzhiy@xzhmu.edu.cn.
Dong GuoJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China. guo@xzhmu.edu.cn.ORCID http://orcid.org/0000-0001-6142-4825
Xuzhou Medical College · CN

Funding

Innovation and Entrepreneurship Training Program for College Students in Jiangsu Province 202210313024ZNatural Science Foundation of Jiangsu Province BK20200106Natural Science Foundation of the Jiangsu Higher Education Institutions of China 20KJA350001Natural Science Foundation of the Jiangsu Higher Education Institutions of China 21KJB350025project of scientific and technological development of traditional Chinese medicine in Jiangsu province MS2021106This project was financially supported by the National Natural Science Foundation of China 22077110This project was financially supported by the National Natural Science Foundation of China 22377103This project was financially supported by the National Natural Science Foundation of China 8234869
6 · The paper itself

Abstract

The discovery of novel chemical entities targeting G protein-coupled receptors (GPCRs) is usually guided by their receptor affinity. However, traditional affinity assay methods and hit identification procedures are usually laborious and expensive. In this work, the type-2 vasopressin receptor (V

Indexed as

GlassImmobilized ProteinsReceptors, VasopressinChromatography, High Pressure LiquidGuanineHumansLigandsMembranes, ArtificialfiberglassGuanineImmobilized ProteinsLigandsMembranes, ArtificialReceptors, VasopressinGlass microfiber membranesHit compoundNatural productSNAP-tagTarget immobilizationType-2 vasopressin receptor

Identifiers

PMID37730920
OpenAlexW4386880139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.