Evidence map›Paper›PMID 37730415›Full record

ArticleBMJ open2023

Can the date of last menstrual period be trusted in the first trimester? Comparisons of gestational age measures from a prospective cohort study in six low-income to middle-income countries.

Archana Patel, Carla M Bann, Vanessa R Thorsten, Sowmya R Rao, Adrien Lokangaka, Antoinette Tshefu Kitoto, Melissa Bauserman, Lester Figueroa, Nancy F Krebs, Fabian Esamai and 10 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01073475 (Global Network for Women's and Children's Health Research Maternal Newborn Health Registry), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01073475 recruitingnot on this map

Global Network for Women's and Children's Health Research Maternal Newborn Health Registry

TypeobservationalSponsorNICHD Global Network for Women's and Children's HealthRan2008 to 2030Enrolled950,000ConditionsPregnancy Outcome Trends in Low-resource Geographic AreasArmsThere is no intervention associated with the parent MNHR study. For the MNHR COVID sub-study, participants will be asked to provide a blood specimen at or near delivery.
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 14 institutions in 7 countries.

Archana PatelLata Medical Research Foundation, Nagpur, Nagpur, Maharashtra, India.
Carla M BannStatistics Division, RTI International, Research Triangle Park, North Carolina, USA cmb@rti.org.ORCID 0000-0001-9305-8305
Vanessa R ThorstenStatistics Division, RTI International, Research Triangle Park, North Carolina, USA.
Sowmya R RaoSchool of Public Health, Boston University, Boston, Massachusetts, USA.
Adrien LokangakaSchool of Public Health, University of Kinshasa, Kinshasa, Congo (the Democratic Republic of the).
Antoinette Tshefu KitotoSchool of Public Health, University of Kinshasa, Kinshasa, Congo (the Democratic Republic of the).
Melissa BausermanSchool of Medicine, University of North Carolina, Chapel Hill, Carolina, USA.
Lester FigueroaInstitute of Nutrition of Central America and Panama, Guatemala, Guatemala, Guatemala.
Nancy F KrebsSchool of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA.
Fabian EsamaiAlupe University College, Busia, Western Kenya, Kenya.
Sherri BucherPediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Sarah SaleemDepartment of Community Health Sciences, The Aga Khan University, Karachi, Sindh, Pakistan.ORCID 0000-0002-6797-8631
Robert L GoldenbergSchool of Medicine, Columbia University, New York, New York, USA.
Elwyn ChombaUniversity of Zambia University Teaching Hospital, Lusaka, Lusaka, Zambia.
Waldemar A CarloDivision of Neonatology, University of Alabama at Birmingham Department of Pediatrics, Birmingham, Alabama, USA.
Shivaprasad GoudarWomen's and Children's Health Research Unit, J N Medical College Belagavi, Belagavi, Karnataka, India.
Richard DermanThomas Jefferson University, Philadelphia, Pennsylvania, USA.
Marion Koso-ThomasEunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA.
Elizabeth McClureStatistics Division, RTI International, Research Triangle Park, North Carolina, USA.ORCID 0000-0001-8659-5444
Patricia L HibberdSchool of Public Health, Boston University, Boston, Massachusetts, USA.
RTI International · USBoston University · USIndiana University School of MedicineUniversity of Kinshasa · CDAga Khan University · PKEunice Kennedy Shriver National Institute of Child Health and Human Development · USInstitute of Nutrition of Central America and Panama · GTLata Medical Research Foundation · INPediatrics and Genetics · USThomas Jefferson University · USUniversity of Alabama at Birmingham · USUniversity of North Carolina at Chapel Hill · USUniversity Teaching Hospital · ZMWomen's & Children's Health Research Institute · AU

Funding

Zika in Pregnancy Supplemental Funding requestU01HD040636 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI MCCLURE, ELIZABETH M · 2001 to 2017
$37.5M
Global Network for Women's and Children's Health Research Data Coordinating CenterU24HD092094 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI Elizabeth M McClure · 2017 to 2026
$17.8M
Interventions to Reduce Infant Mortality and Morbidity in Low Resource SettingsUG1HD078437 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WALDEMAR A. CARLO FONT · 2018 to 2026
$5.6M
The University of North Carolina-Kinshasa School of Public Health Research Partnership in the Democratic Republic of Congo; a Model for Improving Women'sand Children's Health Through ResearchUG1HD076465 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MELISSA SCHWEIKHART BAUSERMAN · 2018 to 2026
$5.6M
Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research UnitUG1HD078439 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Patricia L Hibberd · 2018 to 2026
$5.5M
TJU-JNMC Global Network for Women's & Children's Health Research UnitUG1HD076457 · NICHD · THOMAS JEFFERSON UNIVERSITY · PI RICHARD J DERMAN · 2018 to 2026
$5.5M
Nutrition-specific interventions to improve long-term maternal-child health outcomesUG1HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Edwin Jose Asturias, NANCY F KREBS · 2018 to 2026
$5.4M
The Global Network and Preconception Maternal NutritionU10HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI HAMBIDGE, K MICHAEL, KREBS, NANCY F · 2013 to 2017
$5.1M
Columbia University/Aga Khan University Global Network Research UnitUG1HD078438 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ROBERT L GOLDENBERG · 2018 to 2026
$5.1M
Global Network for Women's and Children's Health ResearchU10HD076461 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI LIECHTY, EDWARD A. · 2013 to 2017
$4.1M
CCHS-JNMC Global Network for Women's & Children's Health Research UnitU10HD076457 · NICHD · THOMAS JEFFERSON UNIVERSITY · PI DERMAN, RICHARD J · 2013 to 2017
$3.7M
Heart Rate Detection during Resuucitation to Reduce Early Neonatal MortalityU10HD078437 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CARLO FONT, WALDEMAR A. · 2013 to 2017
$3.3M
NICHD NIH HHS U01 HD040636NICHD NIH HHS U10 HD076457NICHD NIH HHS U10 HD076461NICHD NIH HHS U10 HD076474NICHD NIH HHS U10 HD078437NICHD NIH HHS U10 HD078438NICHD NIH HHS U10 HD078439NICHD NIH HHS U24 HD092094NICHD NIH HHS UG1 HD076457NICHD NIH HHS UG1 HD076461NICHD NIH HHS UG1 HD076465NICHD NIH HHS UG1 HD076474NICHD NIH HHS UG1 HD078437NICHD NIH HHS UG1 HD078438NICHD NIH HHS UG1 HD078439
6 · The paper itself

Abstract

objectivesWe examined gestational age (GA) estimates for live and still births, and prematurity rates based on last menstrual period (LMP) compared with ultrasonography (USG) among pregnant women at seven sites in six low-resource countries.

designProspective cohort study SETTING AND

participantsThis study included data from the Global Network's population-based Maternal and Newborn Health Registry which follows pregnant women in six low-income and middle-income countries (Democratic Republic of the Congo, Guatemala, India, Kenya, Pakistan and Zambia). Participants in this analysis were 42 803 women, including their 43 230 babies, who registered for the study in their first trimester based on GA estimated either by LMP or USG and had a live or stillbirth with an estimated GA of 20-42 weeks. OUTCOME MEASURES: GA was estimated in weeks and days based on LMP and/or USG. Prematurity was defined as GA of 20 weeks+0 days through 36 weeks+6 days, calculated by both USG and LMP.

resultsOverall, average GA varied ≤1 week between LMP and USG. Mean GA for live births by LMP was lower than by USG (adjusted mean difference (95% CI) = -0.23 (-0.29 to -0.17) weeks). Among stillbirths, a higher GA was estimated by LMP than USG (adjusted mean difference (95% CI)= 0.42 (0.11 to 0.72) weeks). Preterm birth rates for live births were significantly higher when dated by LMP (adjusted rate difference (95% CI)= 4.20 (3.56 to 4.85)). There was no significant difference in preterm birth rates for stillbirths.

conclusionThe small differences in GA for LMP versus USG in the Guatemalan and Indian sites suggest that LMP may be a useful alternative to USG for GA dating during the first trimester until availability of USG improves in those areas. Further research is needed to assess LMP for first-trimester GA dating in other regions with limited access to USG. TRIAL REGISTRATION NUMBER: NCT01073475.

Indexed as

Developing CountriesPremature BirthFemaleGestational AgeHumansInfantInfant, NewbornPregnancyPregnancy Trimester, FirstProspective StudiesStillbirthEpidemiologyNEONATOLOGYOBSTETRICSUltrasonography

Identifiers

PMID37730415
PMCPMC10514667
OpenAlexW4386880681

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.