Evidence map›Paper›PMID 37730290›Full record

ArticleJournal of the American College of Cardiology2023

Chronic Medication Burden After Cardiac Surgery for Pediatric Medicaid Beneficiaries.

Joyce L Woo, Katherine A Nash, Kacie Dragan, Sarah Crook, Matthew Neidell, Stephen Cook, Edward L Hannan, Marshall Jacobs, Andrew B Goldstone, Christopher J Petit and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American College of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors at 18 institutions in 1 country.

Joyce L WooDivision of Pediatric Cardiology, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; Division of Pediatric Cardiology, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
Katherine A NashDivision of Pediatric Critical Care and Hospital Medicine, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
Kacie DraganWagner Graduate School of Public Service, New York University, New York, New York, USA; Interfaculty Initiative in Health Policy, Graduate School of Arts and Sciences, Harvard University, Boston, Massachusetts, USA.
Sarah CrookDivision of Pediatric Cardiology, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
Matthew NeidellDepartment of Health Policy and Management, Mailman School of Public Health, Columbia University, New York, New York, USA.
Stephen CookNew York State Department of Health; Offices of Health Insurance Programs, Albany, New York, USA; Department of Pediatrics, Internal Medicine, and Center for Community Health, University of Rochester Medical Center, Rochester, New York, USA.
Edward L HannanUniversity at Albany School of Public Health, Rensselaer, New York, USA.
Marshall JacobsDivision of Cardiac Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Andrew B GoldstoneDepartment of Cardiothoracic Surgery, NewYork-Presbyterian/Columbia University Irving Medical Center and Weill Cornell Medical Center, New York, New York, USA.
Christopher J PetitInterfaculty Initiative in Health Policy, Graduate School of Arts and Sciences, Harvard University, Boston, Massachusetts, USA.
Robert VincentDivision of Pediatric Cardiology, Westchester Medical Center, Valhalla, New York, USA.
Kathleen Walsh-SpoonhowerDivision of Pediatric Cardiology, Stony Brook Children's Hospital, Stony Brook, New York, USA.
Ralph MoscaDepartment of Cardiothoracic Surgery, New York University, New York, New York, USA.
T K Susheel KumarDepartment of Cardiothoracic Surgery, New York University, New York, New York, USA.
Neil DevejianDivision of Pediatric Cardiothoracic Surgery, Albany Medical College, Albany, New York, USA.
Steven A KamenirDivision of Pediatric Cardiology, Albany Medical College, Albany, New York, USA.
George M AlfierisDivision of Cardiac Surgery, University of Rochester Medical Center, Rochester, New York, USA; Department of Surgery, State University of New York Upstate Medical Center, Syracuse, New York, USA.
Michael F SwartzDivision of Cardiac Surgery, University of Rochester Medical Center, Rochester, New York, USA.
David MeyerDepartments of Cardiothoracic Surgery and Pediatrics, Hofstra-Northwell School of Medicine, Uniondale, New York, USA.
Erin A PaulDivision of Pediatric Cardiology, Icahn School of Medicine at Mt Sinai, New York, New York, USA.
Jane W NewburgerDepartment of Pediatric Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.
John BillingsDivision of Pediatric Critical Care and Hospital Medicine, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
Matthew M DavisDepartment of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Brett R AndersonDivision of Pediatric Cardiology, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA. Electronic address: bra2113@cumc.columbia.edu.
New York State Congenital Heart Surgery Collaborative for Longitudinal Outcomes and Utilization of Resources (CHS-COLOUR)
Columbia University Irving Medical Center · USAlbany Medical Center Hospital · USNew York University · USNorthwestern University · USBoston Children's Hospital · USColumbia University · USCornell University · USHarvard University · USHofstra University · USIcahn School of Medicine at Mount Sinai · USJohns Hopkins University · USNew York State Department of Health · USStony Brook Children's Hospital · USSUNY Upstate Medical University · USThe Graduate Center, CUNY · USUniversity at Albany, State University of New York · USUniversity of Rochester Medical Center · USWestchester Medical Center · US

Funding

Linking State Medicaid and Congenital Heart Surgical Registry Data: Building Capacity to Assess Disparities in Longitudinal Outcomes and Value for Children with Congenital Heart DiseaseR01HL150044 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Brett Romeo Anderson · 2020 to 2026
$5.3M
NHLBI NIH HHS R01 HL150044
6 · The paper itself

Abstract

backgroundCongenital heart defects are the most common and resource-intensive birth defects. As children with congenital heart defects increasingly survive beyond early childhood, it is imperative to understand longitudinal disease burden.

objectivesThe purpose of this study was to examine chronic outpatient prescription medication use and expenditures for New York State pediatric Medicaid enrollees, comparing children who undergo cardiac surgery (cardiac enrollees) and the general pediatric population.

methodsThis was a retrospective cohort study of all Medicaid enrollees age <18 years using the New York State Congenital Heart Surgery Collaborative for Longitudinal Outcomes and Utilization of Resources database (2006-2019). Primary outcomes were total chronic medications per person-year, enrollees per 100 person-years using ≥1 and ≥3 medications, and medication expenditures per person-year. We described and compared outcomes between cardiac enrollees and the general pediatric population. Among cardiac enrollees, multivariable regression examined associations between outcomes and clinical characteristics.

resultsWe included 5,459 unique children (32,131 person-years) who underwent cardiac surgery and 4.5 million children (22 million person-years) who did not. More than 4 in 10 children who underwent cardiac surgery used ≥1 chronic medication compared with approximately 1 in 10 children who did not have cardiac surgery. Medication expenditures were 10 times higher per person-year for cardiac compared with noncardiac enrollees. Among cardiac enrollees, disease severity was associated with chronic medication use; use was highest among infants; however, nearly one-half of adolescents used ≥1 chronic medication.

conclusionsChildren who undergo cardiac surgery experience high medication burden that persists throughout childhood. Understanding chronic medication use can inform clinicians (both pediatricians and subspecialists) and policymakers, and ultimately the value of care for this medically complex population.

Indexed as

Cardiac Surgical ProceduresMedicaidAdolescentChildChild, PreschoolCost of IllnessHeartHumansInfantRetrospective StudiesUnited Stateschronic medication usecongenital heart surgerypublic insurance

Identifiers

PMID37730290
PMCPMC13166102
OpenAlexW4386822293

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.