Evidence map›Paper›PMID 37729682›Full record

ArticleThe International journal on drug policy2023

Mortality, incarceration and cost implications of fentanyl felonization laws: A modeling study.

Alexandra Savinkina, Cole Jurecka, Gregg Gonsalves, Joshua A Barocas

Abstract read
In one paragraph

Article in The International journal on drug policy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexandra SavinkinaDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, United States; Public Health Modeling Unit, Yale School of Public Health, New Haven, CT, United States. Electronic address: Alexandra.savinkina@yale.edu.
Cole JureckaDivisions of General Internal Medicine and Infectious Diseases, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Gregg GonsalvesDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, United States; Public Health Modeling Unit, Yale School of Public Health, New Haven, CT, United States.
Joshua A BarocasDivisions of General Internal Medicine and Infectious Diseases, University of Colorado Anschutz Medical Campus, Aurora, CO, United States. Electronic address: Joshua.Barocas@CUAnschutz.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Making Better Decisions: Policy Modeling for AIDS and Drug AbuseR37DA015612 · NIDA · STANFORD UNIVERSITY · PI DOUGLAS K OWENS · 2019 to 2026
$6.3M
Novel, Adaptive Approaches to Predicting and Responding to Outbreaks of Overdose, HIV and HCV Among People Who Use DrugsDP2DA049282 · NIDA · YALE UNIVERSITY · PI GONSALVES, GREGG STEVEN · 2019 to 2019
$2.5M
Development of a novel community-based high-performance surveillance network for drug useDP2DA051864 · NIDA · UNIVERSITY OF COLORADO DENVER · PI BAROCAS, JOSHUA ADAM · 2020 to 2020
$2.3M
Strategies to reduce serious bacterial infections and overdose among people who inject drugsK01DA051684 · NIDA · UNIVERSITY OF COLORADO DENVER · PI BAROCAS, JOSHUA ADAM · 2020 to 2024
$809k
NCATS NIH HHS UL1 TR001863NIDA NIH HHS DP2 DA049282NIDA NIH HHS DP2 DA051864NIDA NIH HHS K01 DA051684NIDA NIH HHS R37 DA015612
6 · The paper itself

Abstract

backgroundOpioid overdose continues to be a major cause of death in the United States. One effort to control opioid use has been to implement policies that enhance criminalization of opioid possession. Laws to further criminalize possession of fentanyl have been enacted or are under consideration across the country, including at the national level.

objectiveEstimate the long-term effects on opioid death and incarceration resulting from increasingly strict fentanyl possession laws .

designWe built a Markov simulation model to explore the potential outcomes of a 2022 Colorado law which made possession of >1 g of drug with any amount of fentanyl a Level 4 drug felony (and escalation of the previous law, where >4 g of any drug with any amount of fentanyl in possession was considered a felony). The model simulates a cohort of people with fentanyl possession moving through the criminal justice system, exploring the probability of overdose and incarceration under different scenarios, including various fentanyl possession policies and potential interventions.

settingColorado

participantsA simulated cohort of people in possession of fentanyl. MEASUREMENTS: Number of opioid overdose deaths, people incarcerated, and associated costs over 5 years.

resultsWhen >4 g of a drug containing any amount of fentanyl is considered a felony in Colorado, the model predicts 5460 overdose deaths (95% CrI 410-9260) and 2,740 incarcerations for fentanyl possession (95% CrI: 230-10,500) over 5 years. When the policy changes so that >1 g possession of drug with fentanyl is considered a felony, opioid overdose deaths increase by 19% (95% CRI: 16-38%) and incarcerations for possession increase by 98% (CrI: 85-98%). Diversion programs and MOUD in prison help alleviate some of the increases in death and incarceration, but do not completely offset them. LIMITATIONS: The mathematical model is meant to offer broad assessment of the impact of these policies, not forecast specific and exact numerical outcomes.

conclusionsOur model shows that lowering thresholds for felony possession of fentanyl containing drugs can lead to more opioid overdose deaths and incarceration.

Indexed as

Drug OverdoseOpiate OverdoseOpioid-Related DisordersAnalgesics, OpioidFentanylHumansUnited StatesAnalgesics, OpioidFentanylCriminal justiceFentanylOverdoseSimulation modeling

Identifiers

PMID37729682
PMCPMC10840895

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.