Evidence map›Paper›PMID 37729496›Full record

ArticleInorganic chemistry2023

Hydrogen Peroxide Disproportionation Activity Is Sensitive to Pyridine Substitutions on Manganese Catalysts Derived from 12-Membered Tetra-Aza Macrocyclic Ligands.

David M Freire, Hannah M Johnston, Katherine J Smith, Kristof Pota, Magy A Mekhail, Sugam Kharel, Kayla N Green

Abstract read
In one paragraph

Article in Inorganic chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David M FreireDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas 76129, United States.ORCID 0000-0002-0976-2680
Hannah M JohnstonDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas 76129, United States.
Katherine J SmithDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas 76129, United States.ORCID 0009-0004-5730-7342
Kristof PotaDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas 76129, United States.ORCID 0000-0002-9027-0201
Magy A MekhailDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas 76129, United States.
Sugam KharelDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas 76129, United States.
Kayla N GreenDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, Texas 76129, United States.ORCID 0000-0001-8816-7646

Funding

Targeting oxidative stress in neurodegeneration using pyridol-derived small moleculesR15GM123463 · NIGMS · TEXAS CHRISTIAN UNIVERSITY · PI AKKARAJU, GIRIDHAR, CHUMLEY, MICHAEL J · 2018 to 2025
$1.2M
NIGMS NIH HHS R15 GM123463
6 · The paper itself

Abstract

The abundance of manganese in nature and versatility to access different oxidation states have made manganese complexes attractive as catalysts for oxidation reactions in both biology and industry. Macrocyclic ligands offer the advantage of substantially controlling the reactivity of the manganese center through electronic tuning and steric constraint. Inspired by the manganese catalase enzyme, a biological catalyst for the disproportionation of H

Identifiers

PMID37729496
PMCPMC10829483

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.