Evidence map›Paper›PMID 37729371›Full record

ArticleRevista da Associacao Medica Brasileira (1992)2023

miR604A>G gene polymorphism is associated with recurrent pregnancy loss in Turkish women.

Esra Tekcan, Ulas Coban, Mesut Onal, Sengul Tural

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Revista da Associacao Medica Brasileira (1992), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Esra TekcanOndokuz Mayıs University, Faculty of Medicine, Central Laboratory - Samsun, Turkey.ORCID http://orcid.org/0000-0002-6953-9202
Ulas CobanOndokuz Mayıs University, Faculty of Medicine, Department of Obstetrics and Gynecology - Samsun, Turkey.ORCID http://orcid.org/0000-0001-9760-7404
Mesut OnalOndokuz Mayıs University, Faculty of Medicine, Department of Obstetrics and Gynecology - Samsun, Turkey.ORCID http://orcid.org/0000-0003-1222-3386
Sengul TuralOndokuz Mayıs University, Faculty of Medicine, Department of Medical Biology - Samsun, Turkey.ORCID http://orcid.org/0000-0002-8946-8165
Ondokuz Mayıs University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRecurrent pregnancy loss is considerably a reproductive health problem for couples. Genetic, epigenetic, and environmental factors play an important role in the development of recurrent pregnancy loss. While there are many causes, genetic and epigenetic factors are common. In this study, we aimed to examine the association between miR604 (rs2368393) A>G gene polymorphism and the risk of recurrent miscarriage in the Turkish population.

methodsThe study included 250 participants (i.e., 150 patients and 100 controls). DNA samples were isolated from peripheral blood, and polymerase chain reactions and restriction fragment length polymorphism methodologies were applied.

resultsThe genotype distribution and allele frequencies of miR604A>G gene showed statistically significant differences between patients and control groups (p=0.002 and p<0.002, respectively).

conclusionAs a result of the study, we found that the AA genotype and A allele of the miR604A>G gene were statistically significant for the risk of recurrent pregnancy loss in Turkish women.

Indexed as

Abortion, HabitualMicroRNAsPolymorphism, GeneticAllelesFemaleGene FrequencyGenotypeHumansPregnancyMicroRNAs

Identifiers

PMID37729371
PMCPMC10508934
OpenAlexW4386831543

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.