ArticleRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2023
Epidemiologic profile and prevalence of live births with orofacial cleft in Brazil: a descriptive study.
Article in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Antenatal care and childbirth experience among parents of children with orofacial clefts: an observational study.BMC oral health · 2026Observational
- Scientific production on health inequalities using the Brazilian Information System on Live Births: a scoping review.Cadernos de saude publica · 2026Article
- Senses and meanings attributed to Hope by children with orofacial clefts and their family caregivers.Revista da Escola de Enfermagem da U S P · 2026Article
- Analysis of the profile of patients admitted to an orofacial cleft rehabilitation service: An observational study, Cuiabá, 2005-2023.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025Observational
- Orofacial clefts in newborns in Brazil: a time series study, 2010-2021.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025Article
- Geographical distribution and spatial autocorrelation of newborns with orofacial clefts: an epidemiological study, Paraná, 2018-2022.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025Article
- The Global Occurrences of Cleft Lip and Palate in Pediatric Patients and Their Association with Demographic Factors: A Narrative Review.Children (Basel, Switzerland) · 2024Review
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Abstract
objectiveTo describe the epidemiological profile and prevalence of live births with orofacial clefts in Brazil between 1999 and 2020.
methodsDescriptive study. The population corresponded to live births with isolated orofacial clefts in Brazil registered in the Live Birth Information System between 1999 and 2020. Descriptive variables were selected according to their availability and grouped into socioeconomic and demographic, maternal and child health care, and biological variables. Data were submitted to a descriptive analysis using the Software for Statistics and Data Science (STATA).
resultsDuring the period, 33,699 children were born with orofacial clefts, and 82.1% (27,677) of them were isolated clefts. Regarding these cases, the majority were cleft lip and palate (9,619 or 34.7%), followed by cleft palate (9,442 or 34.1%), and by cleft lip (8,616 or 31.3%).
conclusionsLive births with orofacial clefts in Brazil were male, white, with birthweight ≥2,500 g and gestational age ≥37 weeks, born by cesarean section, and with Apgar scores ≥7. The cases were more frequent among mothers who were in their first and single pregnancy and had seven or more prenatal appointments. The mothers were 20 and 29 years old, had eight to ten years of study, and were single. The national prevalence of clefts was 4.24/10,000. The South and Southeast regions of Brazil had the highest prevalence, while the lowest prevalence was recorded in the Northeast and North regions. For the Federative Units, the highest and lowest prevalences were found, respectively, in Paraná and Acre.
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