Evidence map›Paper›PMID 37729202›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

LST-1 is a bifunctional regulator that feeds back on Notch-dependent transcription to regulate

Ahlan S Ferdous, Tina R Lynch, Stephany J Costa Dos Santos, Deep H Kapadia, Sarah L Crittenden, Judith Kimble

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. RNA (New York, N.Y.) · 2025
    Article
  4. Review
  5. Notch controls APC/CScience advances · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. A higher order PUF complex is central to regulation ofbioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ahlan S FerdousDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0002-3610-304X
Tina R LynchDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0003-2730-2669
Stephany J Costa Dos SantosDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0002-4147-6756
Deep H KapadiaDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0009-0009-8220-6179
Sarah L CrittendenDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0003-3375-9825
Judith KimbleDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0001-5622-2073
University of Wisconsin–Madison · US

Funding

Molecular regulation of germline developmentR01GM134119 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI KIMBLE, JUDITH · 2019 to 2022
$2.2M
NIGMS NIH HHS R01 GM134119
6 · The paper itself

Abstract

Notch signaling regulates stem cells across animal phylogeny.

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsCytoplasmCytosolDNA-Binding ProteinsGerm CellsGlucagon-Like Peptide-1 ReceptorHumansCaenorhabditis elegans ProteinsDNA-Binding ProteinsGlucagon-Like Peptide-1 ReceptorLAG-1 protein, C elegansLST-1 protein, C elegansactive transcription siteLAG-1NICDNotch signalingsmFISH

Identifiers

PMID37729202
PMCPMC10523584
OpenAlexW4386884095

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.