Evidence map›Paper›PMID 37728909›Full record

ArticleJournal of clinical microbiology2023

Assessment and validation of enrichment and target capture approaches to improve

B C Mann, K R Jacobson, Y Ghebrekristos, R M Warren, M R Farhat

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

B C MannDepartment of Biomedical Sciences, DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University , Cape Town, South Africa.ORCID 0000-0002-9658-7867
K R JacobsonSection of Infectious Diseases, Boston University School of Medicine , Boston, Massachusetts, USA.
Y GhebrekristosDepartment of Biomedical Sciences, DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University , Cape Town, South Africa.
R M WarrenDepartment of Biomedical Sciences, DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University , Cape Town, South Africa.
M R FarhatDepartment of Biomedical Informatics, Harvard Medical School , Boston, Massachusetts, USA.
South African Medical Research Council · ZABoston University · USHarvard University · USNational Health Laboratory Service · ZA

Funding

Investigating bacterial contributions to TB treatment response: a focus on in-host pathogen dynamicsR01AI155765 · NIAID · HARVARD MEDICAL SCHOOL · PI FARHAT, MAHA · 2020 to 2024
$3.7M
Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL)R01AI147316 · NIAID · BOSTON MEDICAL CENTER · PI JACOBSON, KAREN R · 2019 to 2023
$3.5M
NIAID NIH HHS R01 AI147316NIAID NIH HHS R01 AI155765
6 · The paper itself

Abstract

Within-host

Indexed as

Mycobacterium tuberculosisTuberculosisBase SequenceDNAHumansSputumWhole Genome SequencingDNAdirect sputum sequencingenrichmentmycobacteriatarget capture

Identifiers

PMID37728909
PMCPMC10595060
OpenAlexW4386887113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.