Evidence map›Paper›PMID 37728788›Full record

ArticleThe protein journal2023

Biophysical Characterization of p51 and p66 Monomers of HIV-1 Reverse Transcriptase with Their Inhibitors.

Supaphorn Seetaha, Nuntaporn Kamonsutthipaijit, Maho Yagi-Utsumi, Yanaka Seako, Takumi Yamaguchi, Supa Hannongbua, Koichi Kato, Kiattawee Choowongkomon

Abstract read
PubMed Publisher
In one paragraph

Article in The protein journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Supaphorn SeetahaKU Institute for Advanced Studies, Kasetsart University, Bangkok, 10900, Thailand.
Nuntaporn KamonsutthipaijitSynchrotron Light Research Institute, 111 University Avenue, Muang District, Nakhon Ratchasima, 30000, Thailand.
Maho Yagi-UtsumiExploratory Research Center on Life and Living Systems, Okazaki, Aichi, Japan.
Yanaka SeakoExploratory Research Center on Life and Living Systems, Okazaki, Aichi, Japan.
Takumi YamaguchiExploratory Research Center on Life and Living Systems, Okazaki, Aichi, Japan.
Supa HannongbuaDepartment of Chemistry, Faculty of Science, Kasetsart University, Bangkok, 10900, Thailand.
Koichi KatoExploratory Research Center on Life and Living Systems, Okazaki, Aichi, Japan.
Kiattawee ChoowongkomonKU Institute for Advanced Studies, Kasetsart University, Bangkok, 10900, Thailand. fsciktc@ku.ac.th.ORCID http://orcid.org/0000-0002-2421-7859
National Institutes of Natural Sciences · JPKasetsart University · THSynchrotron Light Research Institute · TH

Funding

Center for Advanced Studies for Agriculture and Food, KU Institute for Advanced Studies, Kasetsart University Center for Advanced Studies for Agriculture and Food, KU Institute for Advanced Studies, Kasetsart UniversityExploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences 19-310Kasetsart University Research and Development Institute FF(KU)17.64The Nanotechnology Platform Program the Nanotechnology Platform Program
6 · The paper itself

Abstract

Human immunodeficiency virus (HIV)-1 reverse transcriptase (HIV-1 RT) is responsible for the transcription of viral RNA genomes into DNA genomes and has become an important target for the treatment of acquired immune deficiency syndrome (AIDS). This study used biophysical techniques to characterize the HIV-1 RT structure, monomer forms, and the non-nucleoside reverse transcriptase inhibitors (NNRTIs) bound forms. Inactive p66

Indexed as

HIV-1HIV Reverse TranscriptaseReverse Transcriptase InhibitorsHumansModels, MolecularNuclear Magnetic Resonance, BiomolecularProtein MultimerizationHIV Reverse Transcriptasereverse transcriptase, Human immunodeficiency virus 1Reverse Transcriptase Inhibitors

Identifiers

PMID37728788
OpenAlexW4386878251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.