Evidence map›Paper›PMID 37728649›Full record

ArticleWiener klinische Wochenschrift2023

[Diagnosis and treatment of focal-segmental glomerulosclerosis-2023].

Philipp Gauckler, Emanuel Zitt, Heinz Regele, Kathrin Eller, Marcus D Säemann, Karl Lhotta, Irmgard Neumann, Michael Rudnicki, Balazs Odler, Andreas Kronbichler and 2 more

Abstract readEnglish Abstract
In one paragraph

Article in Wiener klinische Wochenschrift, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. [Treatment and Prospects of Focal Segmental Glomerulosclerosis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Philipp GaucklerDepartment Innere Medizin IV (Nephrologie und Hypertensiologie), Medizinische Universität Innsbruck, Innsbruck, Österreich. philipp.gauckler@i-med.ac.at.
Emanuel ZittAbteilung für Innere Medizin III (Nephrologie, Dialyse und Hypertensiologie), Akademisches Lehrkrankenhaus Feldkirch, Feldkirch, Österreich.
Heinz RegeleKlinisches Institut für Pathologie, Medizinische Universität Wien, Wien, Österreich.
Kathrin EllerKlinische Abteilung für Nephrologie, Abteilung für Innere Medizin III (Nephrologie, Dialyse und Hypertensiologie), Medizinische Universität Graz, Graz, Österreich.
Marcus D Säemann6.Medizinische Abteilung mit Nephrologie & Dialyse, Klinik Ottakring, Wien, Österreich.
Karl LhottaAbteilung für Innere Medizin III (Nephrologie, Dialyse und Hypertensiologie), Akademisches Lehrkrankenhaus Feldkirch, Feldkirch, Österreich.
Irmgard NeumannVasculitis.at, Wien, Österreich.
Michael RudnickiDepartment Innere Medizin IV (Nephrologie und Hypertensiologie), Medizinische Universität Innsbruck, Innsbruck, Österreich.
Balazs OdlerKlinische Abteilung für Nephrologie, Abteilung für Innere Medizin III (Nephrologie, Dialyse und Hypertensiologie), Medizinische Universität Graz, Graz, Österreich.
Andreas KronbichlerDepartment Innere Medizin 4 (Nephrologie und Hypertensiologie), Medizinische Universität Innsbruck, Innsbruck, Österreich.
Johannes ZschockeInstitut für Humangenetik, Medizinische Universität Innsbruck, Innsbruck, Österreich.
Martin WindpesslAbteilung für Innere Medizin IV, Klinikum Wels-Grieskirchen, Wels, Österreich.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The histopathological term focal-segmental glomerulosclerosis comprises different pathogenic processes with the unifying features of a high proteinuria and the name-giving glomerular lesion pattern seen on light microscopy. A differentiation according to the underlying cause into primary, secondary and genetic forms is therefore of utmost importance. The pathogenesis of primary focal-segmental glomerulosclerosis remains unknown but, like minimal-change disease, an autoimmune-mediated process leading to podocyte damage is assumed. Consequently, the unifying term "podocytopathy" is increasingly being used for both entities. Supportive treatment measures to preserve kidney function are important in all subtypes. In contrast, immunosuppressive treatment is only indicated in primary focal-segmental glomerulosclerosis. Steroid-dependence, steroid-resistance and frequently relapsing disease often complicate disease management and necessitate alternative treatment strategies. Here, the Austrian Society of Nephrology (ÖGN) provides consensus recommendations on how to best diagnose and manage patients with focal-segmental glomerulosclerosis.

Indexed as

Glomerulosclerosis, Focal SegmentalAustriaConsensusDisease ManagementHumansFocal-segmental glomerulosclerosisGlucocorticoidsPodocytopathyProteinuriaRituximabSupportive therapy

Identifiers

PMID37728649
PMCPMC10511576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.