SynthesisAnaesthesiology intensive therapy2023
Identification of risk factors for post-intensive care syndrome in family members (PICS-F) among adult patients: a systematic review.
Synthesis in Anaesthesiology intensive therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 43 citations in OpenAlex.
- The FICUS cluster randomized controlled trial of a family support intervention in adult intensive care units: mental health and family functioning outcomes.Intensive care medicine · 2026Trial
- Effects of The Caregiver Pathway intervention on symptoms of post-intensive care syndrome among family caregivers to critically ill patients: long-term results from a randomized controlled trial.Intensive care medicine · 2025Trial
- Nurse-Led Family Support Intervention for Families of Critically Ill Patients: The FICUS Cluster Randomized Clinical Trial.JAMA internal medicine · 2025Trial
- Surrogate resilience and clinical titration of presence in the open intensive care unit: a systematic narrative synthesis.International journal of nursing studies advances · 2026Review
- Quality of Life in Intensive Care Unit Survivors-Family Member Dyads: A Conceptual Framework and Longitudinal Study Protocol.Nursing in critical care · 2026Article
- Risk Factors for Cardiovascular Disease: Epidemiology, Screening, Prevention, and Therapeutic Interventions.MedComm · 2026Review
- The Validity and Reliability of a Japanese Version of the Family Satisfaction in the Intensive Care Unit Survey: Multicenter Study.JMA journal · 2026Article
- Anxiety and Depression Symptoms in ICU Survivors After COVID-19.Nursing in critical care · 2026Article
- "It was torture for him, and it was torture for us to see him like that": understanding multiple ICU-related triggers of family PTSD symptoms-a qualitative thematic study.Intensive care medicine · 2026Article
- [Complex family interventions in intensive care units: state of knowledge and future directions].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Review
- [Ethically challenging determination of treatment goals in the intensive care unit: reasons, frequency and possible solutions].Die Anaesthesiologie · 2026Review
- Interventions to improve mental health in caregivers of adult intensive care patients: a systematic review.BMC nursing · 2026Article
- The Effects of Digital Health Interventions for Family Members in Intensive Care Units: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Review
- Association between the clinical status of patients admitted to Intensive Care and the emotional state of their next of kin: a cross-sectional study.Journal of anesthesia, analgesia and critical care · 2026Article
- Evaluation of a Tablet-Based Emotion Regulation Intervention for Surrogate Decision-Makers of Patients With Critical Illness: Pilot Nonrandomized Trial.JMIR formative research · 2026Article
- Gender-specific associations between personality traits and mental health status of intensive care unit patients' family members.European journal of medical research · 2026Article
- Nursing Intervention to Support Psychological Recovery Among Intensive Care Patients and Their Families: A Systematic Review with Narrative Synthesis.Journal of multidisciplinary healthcare · 2026Review
- [Challenge healthcare system: spotlight on PICS].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Review
- Post-COVID-19 Consequences in Relatives of Severely Ill Patients: Results of the Prospective Multicenter NeNeSCo Study.Clinical nursing research · 2025Article
- Hostility in the ICU Waiting Room: Extrapunitive and Intropunitive Reactions Among Family Members.Healthcare (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRelatives of critically ill patients who either die or survive the intensive care unit (ICU) may develop substantial mental health problems that are collectively defined as post-intensive care syndrome in family (PICS-F). MATERIAL AND
methodsBy using a systematised search strategy we included studies that focused on PICS-F in relatives of adult ICU patients and reported the risk factors associated with its development. The search was conducted within PubMed, Embase, SCOPUS, clinicaltrials.gov, and Cochrane Library on the 23 August 2022. PRISMA 2020 guidelines were implemented for appropriate reporting. The objective was to document all possible risk factors associated with the development of PICS-F.
resultsWe included 51 papers covering 9302 relatives. The frequency of PICS-F varied between 2.5 and 69%. We identified 51 different risk factors of PICS-F, among which we distinguished patient-related ( n = 16), relative-related ( n = 27), and medical staff-related ( n = 8) risk factors. Among 21 studies of the highest quality, we identified the 33 variables associated with the development of PICS-F, of which younger age of a patient, death of a patient, depression in relatives during the ICU stay, history of mental disorders in relatives, being a female relative, being a spouse, and having low satisfaction with communication and care in the ICU were the most commonly reported risk factors.
conclusionsPICS-F is a highly frequent phenomenon that can be exacerbated by several risk factors. Special attention should be paid to relatives of younger patients with worse prognosis and with the following relative-related risk factors: female sex, being a spouse, and history of mental health disorders. Finally, the medical staff play a role in preventing the PICS-F development, not only by maintenance of proper communication, but also by early identification of relatives prone to PICS-F.
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