Evidence map›Paper›PMID 37728336›Full record

ArticleJournal of clinical microbiology2023

Sensitivity of rapid antigen tests against SARS-CoV-2 Omicron and Delta variants.

Anuradha Rao, Adrianna Westbrook, Leda Bassit, Richard Parsons, Eric Fitts, Morgan Greenleaf, Kaleb McLendon, Julie A Sullivan, William O'Sick, Tyler Baugh and 13 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. The New Normal: Delayed Peak SARS-CoV-2 Viral Loads Relative to Symptom Onset and Implications for COVID-19 Testing Programs.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 5 institutions in 1 country.

Anuradha Rao *The Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
Adrianna Westbrook *The Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
Leda BassitThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
Richard ParsonsThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
Eric FittsDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine , Atlanta, Georgia, USA.
Morgan GreenleafThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
Kaleb McLendonThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
Julie A SullivanThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
William O'SickThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
Tyler BaughThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
Heather B BowersThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
Filipp FrankDepartment of Biochemistry, Emory University School of Medicine , Atlanta, Georgia, USA.
Ethan WangDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine , Atlanta, Georgia, USA.
Mimi LeDepartment of Pediatrics, Emory University School of Medicine , Atlanta, Georgia, USA.
Jennifer FredianiThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
Pavitra RoychoudhuryDepartment of Laboratory Medicine, University of Washington , Seattle, Washington, USA.
Alexander L GreningerDepartment of Laboratory Medicine, University of Washington , Seattle, Washington, USA.
Robert JerrisChildren's Healthcare of Atlanta , Atlanta, Georgia, USA.
Nira R PollockDepartment of Laboratory Medicine, Boston Children's Hospital and Harvard Medical School , Boston, Massachusetts, USA.
Eric A OrtlundThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
John D RobackThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
Wilbur A LamThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies , Atlanta, Georgia, USA.
Anne PiantadosiDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine , Atlanta, Georgia, USA.ORCID 0000-0002-5942-1534
Emory University · USUniversity of Washington · USBoston Children's Hospital · USChildren's Healthcare of Atlanta · USGeorgia Institute of Technology · US

Funding

Technology Training and Dissemination CoreU54EB027690 · NIBIB · EMORY UNIVERSITY · PI Wilbur A Lam · 2018 to 2026
$96.1M
Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
NCATS NIH HHS UL1 TR002378NIBIB NIH HHS U54 EB027690
6 · The paper itself

Abstract

Rapid antigen tests (RATs) have become an invaluable tool for combating the COVID-19 pandemic. However, concerns have been raised regarding the ability of existing RATs to effectively detect emerging SARS-CoV-2 variants. We compared the performance of 10 commercially available, emergency use authorized RATs against the Delta and Omicron SARS-CoV-2 variants using both individual patient and serially diluted pooled clinical samples. The RATs exhibited lower sensitivity for Omicron samples when using PCR cycle threshold (C

Indexed as

COVID-19SARS-CoV-2HumansPandemicsRNARNArapid antigen testSARS-CoV-2

Identifiers

PMID37728336
PMCPMC10654096
OpenAlexW4386878375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.