Evidence map›Paper›PMID 37728335›Full record

ArticleMicrobiology spectrum2023

Disentangling the interactions between nasopharyngeal and gut microbiome and their involvement in the modulation of COVID-19 infection.

Leonardo Mancabelli, Giuseppe Taurino, Andrea Ticinesi, Tecla Ciociola, Federica Vacondio, Christian Milani, Federico Fontana, Gabriele Andrea Lugli, Chiara Tarracchini, Giulia Alessandri and 9 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Observational
  2. Observational
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 1 institution in 1 country.

Leonardo MancabelliDepartment of Medicine and Surgery, University of Parma , Parma, Italy.
Giuseppe TaurinoDepartment of Medicine and Surgery, University of Parma , Parma, Italy.
Andrea TicinesiDepartment of Medicine and Surgery, University of Parma , Parma, Italy.
Tecla CiociolaDepartment of Medicine and Surgery, University of Parma , Parma, Italy.
Federica VacondioInterdepartmental Research Centre "Microbiome Research Hub", University of Parma , Parma, Italy.
Christian MilaniInterdepartmental Research Centre "Microbiome Research Hub", University of Parma , Parma, Italy.ORCID 0000-0002-5062-3164
Federico FontanaLaboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma , Parma, Italy.
Gabriele Andrea LugliLaboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma , Parma, Italy.
Chiara TarracchiniLaboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma , Parma, Italy.
Giulia AlessandriLaboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma , Parma, Italy.
Alice ViappianiGenProbio srl , Parma, Italy.
Massimiliano BianchiDepartment of Medicine and Surgery, University of Parma , Parma, Italy.
Antonio NouvenneDepartment of Medicine and Surgery, University of Parma , Parma, Italy.
Alfredo Antonio ChettaDepartment of Medicine and Surgery, University of Parma , Parma, Italy.
Francesca TurroniInterdepartmental Research Centre "Microbiome Research Hub", University of Parma , Parma, Italy.ORCID 0000-0001-5363-0231
Tiziana MeschiDepartment of Medicine and Surgery, University of Parma , Parma, Italy.
Marco MorInterdepartmental Research Centre "Microbiome Research Hub", University of Parma , Parma, Italy.
Ovidio BussolatiDepartment of Medicine and Surgery, University of Parma , Parma, Italy.
Marco VenturaInterdepartmental Research Centre "Microbiome Research Hub", University of Parma , Parma, Italy.ORCID 0000-0002-4875-4560
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceThe human microbiota is reported to play a major role in the regulation of host health and immunity, suggesting a possible impact on the severity of COVID-19 disease. This preliminary study investigated the possible correlation between nasopharyngeal microbiota and COVID-19 infection. In detail, the analysis of the nasopharyngeal microbiota of hospitalized Italian patients with and without COVID-19 infection suggested a positive association of several microbial species with the severity of the disease and highlighted a sharing of several bacteria species with the respective fecal samples. Moreover, the metabolic analyses suggested a possible impact of the microbiome on the host's immune response and the disease severity.

Indexed as

COVID-19gut microbiomeinflammationmicrobiomenasopharyngeal microbiota

Identifiers

PMID37728335
PMCPMC10581039
OpenAlexW4386878084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.