ArticleEuropean thyroid journal2023
Influence of metabolic syndrome and lifestyle factors on thyroid nodules in Chinese adult men: a cross-sectional study.
Article in European thyroid journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 12 citations in OpenAlex.
- Causal Association of Dietary Habits With Thyroid Diseases: Univariate and Multivariate Mendelian Randomization Studies.Food science & nutrition · 2026Article
- Development and validation of a predictive nomogram for high-risk thyroid nodules: a retrospective analysis of sedentary time, insomnia, and elevated weight.Frontiers in oncology · 2026Article
- Association of age, BMI and their interaction with thyroid nodules in patients with type 2 diabetes mellitus: a cross-sectional study.Frontiers in endocrinology · 2026Article
- Environmental exposure to mixtures of per- and polyfluoroalkyl substances in Northeast China: exploring links to nodular goiter and papillary thyroid carcinoma.Environmental health : a global access science source · 2025Article
- Evaluating the association between pulse wave velocity, augmentation index, serum TSH levels, and the prevalence of thyroid nodules in a Persian adult cohort: a cross-sectional study.Journal of diabetes and metabolic disorders · 2025Article
- Prevalence and predictors of thyroid nodules among adults: analyzing the association with metabolic syndrome in a cross-sectional study.BMC endocrine disorders · 2025Article
- Nomogram Prediction Model of Thyroid Nodule in Healthcare Professionals: Based on Physical and Psychological Risk Factors.Risk management and healthcare policy · 2025Article
- Analysis of the detection rate and related factors of thyroid nodules in the healthy population.Open life sciences · 2025Article
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- A study on the correlation of thyroid nodules with METS-IR and SII in a population undergoing health checkups.Frontiers in endocrinology · 2025Article
- Pituitary-Thyroid Hormones and Related Indices in Euthyroid Type 2 Diabetes: Association With Thyroid Nodules.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Risk factors for thyroid nodules in a health examination population: a cross-sectional study and development of a simplified predictive model.Frontiers in endocrinology · 2025Article
- Establishment and validation of a multivariate logistic model for risk factors of thyroid nodules using lasso regression screening.Frontiers in endocrinology · 2024Article
- Analysis of Prevalence of Thyroid Nodules and Related Factors in Physical Examination Population in a Hospital in Jinan [Letter].Journal of multidisciplinary healthcare · 2024Article
- Machine learning to predict the occurrence of thyroid nodules: towards a quantitative approach for judicious utilization of thyroid ultrasonography.Frontiers in endocrinology · 2024Article
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Given the high prevalence of thyroid nodules and the potential for malignancy, it is imperative to understand the various factors that contribute to their development. This study aimed to explore the relationship between metabolic syndrome, lifestyle, and thyroid nodules in adult men in southern China. Methods: This study enrolled a total of 183,990 subjects at a medical examination center in a general hospital in southern China between January 1, 2015, and December 31, 2020. Multivariate logistic regression analysis was utilized to evaluate the relationship between metabolic syndrome, lifestyle factors, and thyroid nodules. Furthermore, structural equation modeling elucidated the intricate relationships among these variables. Results: The prevalence of thyroid nodules among Chinese adult males was 14.9%. Several factors were identified as risk factors for thyroid nodules, including advanced age, irregular meal time, smoking or quitting smoking, quitting drinking, heavy manual labor, hypertension, diabetes, dyslipidemia and centripetal obesity, and those belonging to ethnic minorities and drinking alcohol were found to be protective factors against thyroid nodules. Structural equation modeling highlighted metabolic syndrome's mediating role amidst lifestyle influences on thyroid nodules. Conclusion: The prevalence of thyroid nodules in Chinese adult males is relatively moderate to low. The factors identified in this study can help clinicians identify high-risk patients and develop targeted screening strategies for the timely detection of thyroid nodules. However, further mechanistic research and longitudinal studies are necessary to explore the underlying causes and establish causal relationships.
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