ArticleCureus2023
The Epidemiological Profile and Predisposing Factors of Microbial Keratitis Over a 10-Year Period at a Tertiary Hospital in Central Saudi Arabia.
Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- From pathogen to prognosis: microbial keratitis spectrum and treatment outcomes in a 5-Year tertiary center experience.Journal of ophthalmic inflammation and infection · 2025Article
- Ion-paired moxifloxacin nanocrystal formulation improves treatment and prevention of ocular infection.Journal of controlled release : official journal of the Controlled Release Society · 2025Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the demographic and predisposing factors and clinical presentation of microbial keratitis (MK) patients over 10 years at a tertiary hospital in central Saudi Arabia.
methodIn 2020, a retrospective review of data from clinical and pathology departments from 2010 to 2019 was conducted. Demography includes age, gender, residence, and the risk factor of microbial keratitis, clinical features, and organism profile as number and percentage.
resultWe reviewed 181 eyes of 179 patients with microbial keratitis. The mean age was 40.1 years. Contact lens usage (55; 30%), ocular trauma (30; 16.5%), and ocular surface diseases (42; 23.2%) were the main predisposing factors. Hypopyon was noted in 60 (33%) eyes, impaired vision at presentation was observed in 78 (43%) eyes, and endophthalmitis with microbial keratitis was noted in eight (4.4%) eyes at presentation. Ninety-eight (54,1%) cases were culture positive, while gram-positive organisms were seen in 50 (27.6%) eyes, gram-negative organisms in 35 (19.3%) patients, and fungi in 13 (7.2%) patients. Microbial keratitis was central in 67 (37%), paracentral in 94 (52%), and peripheral in 20 (11.3%) patients. All instances of fungal keratitis occurred in the eyes of men who work in the agriculture field.
conclusionStandard operating procedures to manage microbial keratitis at primary and secondary eye care levels are recommended. Health promotion to prevent trauma, appropriate use of contact lens, and early treatment could prevent the incidence of microbial keratitis.
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