Evidence map›Paper›PMID 37727784›Full record

ArticleFrontiers in immunology2023

Targeted delivery of autoantigen to dendritic cells prevents development of spontaneous uveitis.

Izabela P Klaska, Tian Yu, Rosie Fordyce, Koju Kamoi, Richard J Cornall, Cristina Martin-Granados, Lucia Kuffova, John V Forrester

Abstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Izabela P KlaskaInstitute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Tian YuInstitute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Rosie FordyceInstitute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Koju KamoiInstitute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Richard J CornallNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Cristina Martin-GranadosInstitute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Lucia KuffovaInstitute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
John V ForresterInstitute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Restoration of immunological tolerance to self antigens has been a major drive in understanding the mechanisms of, and developing new treatments for, autoimmune and autoinflammatory disease. Sessile dendritic cells (DC) are considered the main instruments underpinning immunological tolerance particularly the CD205

Indexed as

AntibodiesAutoantigensAdoptive TransferAnimalsDendritic CellsMiceReceptors, Antigen, T-CellAntibodiesAutoantigensReceptors, Antigen, T-CellautoimmuneDEC205dendritic cellsfusion proteinhen egg lysozymeuveitis

Identifiers

PMID37727784
PMCPMC10505613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.