Evidence map›Paper›PMID 37727635›Full record

ReviewFrontiers in nutrition2023

Evidence or no evidence for essential fatty acids in the treatment of autism spectrum disorders?

Rouzha Zlatanova Pancheva, Silviya Nikolova, Asena Serbezova, Krassimira Zaykova, Desislava Zhelyazkova, Lubomir Dimitrov

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rouzha Zlatanova PanchevaDepartment of Hygiene and Epidemiology, Faculty of Public Health, Medical University of Varna "Prof. Dr. Paraskev Stoyanov", Varna, Bulgaria.
Silviya NikolovaDepartment of Social Medicine, Faculty of Public Health, Medical University of Varna "Prof. Dr. Paraskev Stoyanov", Varna, Bulgaria.
Asena SerbezovaDepartment of Health Policy and Management, Faculty of Public Health, Medical University of Sofia, Sofia, Bulgaria.
Krassimira ZaykovaFaculty of Medicine, Medical University of Varna "Prof. Dr. Paraskev Stoyanov", Varna, Bulgaria.
Desislava ZhelyazkovaFaculty of Medicine, Medical University of Varna "Prof. Dr. Paraskev Stoyanov", Varna, Bulgaria.
Lubomir DimitrovDepartment of Hygiene and Epidemiology, Faculty of Public Health, Medical University of Varna "Prof. Dr. Paraskev Stoyanov", Varna, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorders (ASDs) are a group of neurodevelopmental disorders that affect social communication, behavior, and sensory processing, in which PUFAs are considered important. This mini-review article aims to investigate the current evidence regarding the use of essential fatty acids (EFAs) in the treatment of autism spectrum disorders (ASDs). The study examines various research studies, related to EFAs, their benefits, and their role in ASD treatment. The article focuses on exploring the potential mechanisms underlying the effects of EFAs on ASDs, including their anti-inflammatory, antioxidant, and neuroprotective properties. Furthermore, the study discusses limitations and challenges associated with the use of EFAs in ASD treatment, including variability in dosage and duration of treatment. The results of this review indicate that while some studies suggest a positive effect of EFAs on ASD symptoms, there is currently insufficient evidence to support their routine use as a stand-alone treatment for ASD. The need for further research to better understand the potential benefits and limitations of EFAs in ASD treatment is highlighted.

Indexed as

autismchildessential fatty acidsinterventionsupplementation

Identifiers

PMID37727635
PMCPMC10505929

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.