Evidence map›Paper›PMID 37727335›Full record

ArticleGland surgery2023

ERα promotes

Quhui Wang, Nannan Zhang, Xiaobing Yang, Shichun Feng, Feiran Wang, Wei Zhang, Zhixian He

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gland surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Quhui Wang *Department of General Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.
Nannan Zhang *Department of General Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.
Xiaobing Yang *Department of General Surgery, Huaian Hospital of Huaian City, Huaian, China.
Shichun FengDepartment of General Surgery, The Second Affiliated Hospital of Nantong University, Nantong, China.
Feiran WangDepartment of General Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.
Wei ZhangDepartment of General Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.
Zhixian HeDepartment of General Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Estrogen plays a crucial role in the tumorigenesis of breast cancer (BC), and epigenetic modification by SUMOylation is essential for cancer development. However, the mechanism underlying estrogen's actions on protein SUMOylation and its effect on BC development are still incompletely understood. Methods: Results: E2 promoted Conclusions: Collectively, our results showed that E2 promoted the transcription and protein expression of

Indexed as

Breast cancer (BC)estrogen receptor (ER)RasSUMO1SUMOylation

Identifiers

PMID37727335
PMCPMC10506115

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.