ArticleGland surgery2023
Implications of isthmic location as a risk factor in papillary thyroid carcinoma.
Article in Gland surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Clinical outcomes of lobectomy versus isthmusectomy for clinically node-negative solitary isthmic papillary thyroid microcarcinoma: a retrospective cohort study.Gland surgery · 2026Article
- Exploratory Statistical Analyses of Clinical and Biochemical Factors for Differentiated Thyroid Cancer from a Romanian Cohort.Cancers · 2026Article
- Thermal ablation for papillary thyroid carcinoma in the isthmus: a systematic review and meta-analysis.Gland surgery · 2025Article
- Lobectomy with ipsilateral central lymph node dissection might be an appropriate surgical method for select cases of isthmic papillary thyroid carcinoma: a retrospective study with propensity scores matching analysis.Frontiers in endocrinology · 2025Article
- Risk factors associated with high-risk nodal disease in patients considered for active surveillance of papillary thyroid microcarcinoma without extrathyroidal extension.Gland surgery · 2023Article
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Authors and funding
4 authors.
Funding
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Abstract
Background: Papillary thyroid carcinoma (PTC) located in the isthmus generally has been known to have more extrathyroidal extension (ETE), lymph node involvement, and multifocality. The purpose of this study was to determine the clinical significance of an isthmic location of PTC. Methods: The records of 160 patients who underwent a total thyroidectomy due to a single, dominant isthmic PTC were retrospectively reviewed. The characteristics of isthmic cancer were compared with those of unilateral-lobar cancer in a PTC cohort at Seoul St. Mary's hospital. After propensity score matching for age, sex, and tumor size, 160 isthmic PTCs and 800 unilateral-lobar PTCs were compared. The clinicopathologic characteristics were analyzed to evaluate the prognostic significance of an isthmic tumor location. Results: The isthmic group was significantly older (49.6 Conclusions: Isthmic location is not an independent risk factor for aggressive clinicopathologic features and is not related to PTC recurrence.
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