Evidence map›Paper›PMID 37727187›Full record

ArticleCureus2023

Early Trends to Show the Efficacy of Cordyceps militaris in Mild to Moderate COVID Inflammation.

Siddharth Dubhashi, Sagar Sinha, Sankalp Dwivedi, Jaishree Ghanekar, Sameer Kadam, Parineeta Samant, Vibha Datta, Sarman Singh, Irshad H Chaudry, Padma Gurmet and 4 more

Abstract read
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The GenusLife (Basel, Switzerland) · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Siddharth DubhashiSurgery, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.
Sagar SinhaEmergency Medicine, Mahatma Gandhi Mission (MGM) Medical College and Hospital, Navi Mumbai, IND.
Sankalp DwivediGeneral Surgery, Maharishi Markandeshwar (MM) Institute of Medical Sciences and Research, Mullana, IND.
Jaishree GhanekarInternal Medicine, Mahatma Gandhi Mission (MGM) Medical College and Hospital, Navi Mumbai, IND.
Sameer KadamCardiovascular Surgery, Mahatma Gandhi Mission (MGM) Medical College and Hospital, Navi Mumbai, IND.
Parineeta SamantBiochemistry, Mahatma Gandhi Mission (MGM) Medical College and Hospital, Navi Mumbai, IND.
Vibha DattaPathology, All India Institute of Medical Sciences, Nagpur, Nagpur, IND.
Sarman SinghMedical Science and Engineering Research (MEDSER) Center, Indian Institute of Science Education and Research (IISER), Bhopal, IND.
Irshad H ChaudrySurgery, University of Alabama, Birmingham, USA.
Padma GurmetMiscellaneous, National Institute of Sowa-Rigpa, Leh, IND.
Harshawardhan KelkarMedicine, Ayurarogya, Kelkar Hospital, Nashik, IND.
Rakesh MishraNeurosurgery, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Sagar GalwankarEmergency Medicine, Florida State University College of Medicine, Sarasota, USA.
Amit AgrawalNeurosurgery, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/objective Cordyceps enhances animal survival against influenza by boosting the immune system. In animal studies, it also had anti-inflammatory and preventive properties. Cordyceps stimulates the immune system by increasing the activity and production of various immune cells. Some studies have shown the role of Cordyceps in the novel SARS-CoV-2 virus responsible for the COVID-19 pandemic, in addition to other respiratory diseases caused by the Picorna viruses, SARS-CoV, MERS-CoV, and Influenza viruses. However, it remains unknown whether this food supplement is safe and has anti-inflammatory effects in patients with COVID-19. Therefore, the objectives of this study were to evaluate the use and efficacy of Cordyceps capsules as an adjunct to standard treatment in patients with mild (symptomatic) to moderate COVID-19 infection. Methods A randomised, double-blind, placebo-controlled study was conducted to evaluate the efficacy and safety of Cordyceps capsules (a food supplement) 500 mg as adjuvant therapy in patients with COVID-19. The rationale for dose selection was as per the existing evidence from toxicity studies. The inclusion criteria were patients with either a mild or moderate COVID-19 infection. Clinical features suggestive of dyspnoea or hypoxia, fever, and cough, including SpO

Indexed as

cordycepscordyceps militariscovid-19cytokinesplant based immunotherapy

Identifiers

PMID37727187
PMCPMC10505833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.