Evidence map›Paper›PMID 37726886›Full record

ReviewCell adhesion & migration2023

Overview of hepatocellular carcinoma: from molecular aspects to future therapeutic options.

Sugan Panneerselvam, Cornelia Wilson, Prem Kumar, Dinu Abirami, Jayakrishna Pamarthi, Mettu Srinivas Reddy, Joy Varghese

Open access · goldAbstract readReview
In one paragraph

Review in Cell adhesion & migration, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Effect ofIranian journal of basic medical sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sugan PanneerselvamDepartment of Hepatology and Transplant Hepatology, Gleneagles Global Health City, Chennai, Tamil Nadu, India.ORCID 0000-0002-9698-3843
Cornelia WilsonNatural and Applied Sciences, School of Psychology and Life Sciences, Canterbury Christ Church University, Discovery Park, Sandwich, UK.
Prem KumarDepartment of Hepatology and Transplant Hepatology, Gleneagles Global Health City, Chennai, Tamil Nadu, India.
Dinu AbiramiDepartment of Gastroenterology, Gleneagles Global Health City, Chennai, Tamil Nadu, India.
Jayakrishna PamarthiMulti-Disciplinary Research Unit, Madras Medical College, Chennai, Tamil Nadu, India.
Mettu Srinivas ReddyThe Director and Head, Liver Transplant and HPB surgery, Gleneagles Global Health City, Chennai, Tamil Nadu, India.
Joy VargheseDepartment of Gastroenterology, Gleneagles Global Health City, Chennai, Tamil Nadu, India.
Global Hospitals · INCanterbury Christ Church University · GBMadras Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the seventh most highly prevalent malignant tumor globally and the second most common cause of mortality. HCC develops with complex pathways that occur through multistage biological processes. Non-alcoholic fatty liver disease, metabolic-associated fatty liver disease, alcoholic liver disease, autoimmune hepatitis, hepatitis B, and hepatitis C are the causative etiologies of HCC. HCC develops as a result of epigenetic changes, protein-coding gene mutations, and altered signaling pathways. Biomarkers and potential therapeutic targets for HCC open up new possibilities for treating the disease. Immune checkpoint inhibitors are included in the treatment options in combination with molecular targeted therapy.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsHumansMolecular Targeted TherapyMutationcell signaling pathwaysCirculating tumour cellHCC biomarkersimmunotherapymulti-omics technology

Identifiers

PMID37726886
PMCPMC10512929
OpenAlexW4386878388

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.