Evidence map›Paper›PMID 37726455›Full record

ArticleThe international journal of cardiovascular imaging2022

The variability of 2D and 3D transthoracic echocardiography applied in a general population : Intermodality, inter- and intraobserver variability.

Filip Lyng Lindgren, Bhupendar Tayal, Kristian Bundgaard Ringgren, Peter Ascanius Jacobsen, Kristian Hay Kragholm, Tomas Zaremba, Niels Holmark Andersen, Rasmus Møgelvang, Tor Biering-Sørensen, Andreas Hagendorff and 3 more

Abstract read
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In one paragraph

Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Myocarditis Prognostic Score: A New Risk Assessment Tool.Journal of cardiovascular development and disease · 2026
    Article
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Review
  11. Clinical, Safety, and Engineering Perspectives on Wearable Ultrasound Technology: A Review.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Filip Lyng LindgrenDepartment of Cardiology, Aalborg University Hospital, Aalborg, Denmark. f.lindgren@rn.dk.ORCID http://orcid.org/0000-0003-1939-580X
Bhupendar TayalDepartment of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Kristian Bundgaard RinggrenDepartment of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Peter Ascanius JacobsenClinical Institute, Aalborg University, Aalborg, Denmark.
Kristian Hay KragholmDepartment of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Tomas ZarembaDepartment of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Niels Holmark AndersenDepartment of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Rasmus MøgelvangCentre for Cardiac, Vascular, Pulmonary and Infectious Diseases, Rigshospitalet, Copenhagen, Denmark.
Tor Biering-SørensenCardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Herlev and Gentofte Hospital, Copenhagen, Denmark.
Andreas HagendorffLaboratory of Echocardiography, Department of Cardiology-Angiology, University of Leipzig, Leipzig, Germany.
Peter SchnohrThe Copenhagen City Heart Study, Frederiksberg Hospital, Frederiksberg, Denmark.
Gorm JensenThe Copenhagen City Heart Study, Frederiksberg Hospital, Frederiksberg, Denmark.
Peter SøgaardDepartment of Cardiology, Aalborg University Hospital, Aalborg, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Assessment of the left ventricular (LV) function by three-dimensional echocardiography (3DE) is potentially superior to 2D echo echocardiography (2DE) for LV performance assessment. However, intra- and interobserver variation needs further investigation. We examined the intra- and interobserver variability between 2 and 3DE in a general population. In total, 150 participants from the Copenhagen City Heart Study were randomly chosen. Two observers assessed left ventricular ejection fraction (LVEF), end-diastolic (EDV) and end-systolic volumes (ESV) by 2DE and 3DE. Inter-, intraobserver and intermodality variabilities are presented as means of difference (MD), limits of agreement (LoA), coefficient of correlation (r), intraclass correlation coefficients (ICC). The lowest MD and LoA and highest r- and ICC-values was generally seen among the 3D acquisitions, with the 3D EDV interobserver as the best performing estimate (r = 0.95, ICC = 0.94). The largest MD, LoA and lowest r- and ICC-values was found in the interobserver 2D LVEF (r = 0.76, ICC = 0.63. For the intraobserver analysis, there were statistically significant differences between observations for all but 3DE EDV (p = 0.06). For interobserver analysis, there were statistically significant differences between observers for all estimates but 2DE EDV (p = 0.11), 3D ejection fraction (p = 0.9), 3DE EDV (p = 0.11) and 3D ESV (p = 0.15). Three-dimensional echocardiography is more robust and reproducible than 2DE and should be preferred for assessment of LV function.

Indexed as

Echocardiography, Three-DimensionalVentricular Function, LeftEchocardiographyHumansObserver VariationPredictive Value of TestsStroke VolumeCardiac imaging techniquesHealth surveysHeart failureLeft ventricular functionUrban population

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.