Evidence map›Paper›PMID 37726309›Full record

ArticleScientific reports2023

Breastmilk from COVID-19 negative lactating mothers shows neutralizing activity against SARS-COV-2.

Daniela Morniroli, Lucia Signorini, Maria Dolci, Giulia Vizzari, Andrea Ronchi, Carlo Pietrasanta, Lorenza Pugni, Fabio Mosca, Serena Delbue, Maria Lorella Gianni

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Daniela Morniroli *Department of Clinical Sciences and Community Health, University of Milan, Via Della Commenda 12, 20122, Milan, Italy. daniela.morniroli@unimi.it.
Lucia Signorini *Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Maria DolciDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Giulia VizzariFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, NICU, Milan, Italy.
Andrea RonchiFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, NICU, Milan, Italy.
Carlo PietrasantaDepartment of Clinical Sciences and Community Health, University of Milan, Via Della Commenda 12, 20122, Milan, Italy.
Lorenza PugniFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, NICU, Milan, Italy.
Fabio MoscaDepartment of Clinical Sciences and Community Health, University of Milan, Via Della Commenda 12, 20122, Milan, Italy.
Serena DelbueDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Maria Lorella GianniDepartment of Clinical Sciences and Community Health, University of Milan, Via Della Commenda 12, 20122, Milan, Italy.
University of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breastmilk protects newborns from infections through specific and nonspecific compounds. This study investigated the neutralizing activity against SARS-CoV-2 of breastmilk from SARS-CoV-2 negative, unvaccinated mothers, and compared it to that from infected nursing mothers. We enrolled women after COVID-19 swab testing results upon maternity admission, and divided them into two groups: group A, COVID-19-positive mothers, and group B, negative mothers. Breastmilk was randomly sampled at 2, 7, and 20 days postpartum. We collected 19 samples for Group A and 41 for Group B. A microneutralization assay was used to determine the 50% neutralization (NT

Indexed as

COVID-19Milk, HumanAntibodies, NeutralizingFemaleHumansInfant, NewbornLactationMothersPregnancySARS-CoV-2Antibodies, Neutralizing

Identifiers

PMID37726309
PMCPMC10509262
OpenAlexW4386874109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.