Evidence map›Paper›PMID 37725986›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2024

Living Longer But Frailer? Temporal Trends in Life Expectancy and Frailty in Older Swedish Adults.

Clare Tazzeo, Debora Rizzuto, Amaia Calderón-Larrañaga, Serhiy Dekhtyar, Alberto Zucchelli, Xin Xia, Laura Fratiglioni, Davide Liborio Vetrano

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Mortality Dynamics in Low-Mortality Countries: An Introduction to the Special Issue.European journal of population = Revue europeenne de demographie · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Dynamics of multimorbidity, health expectancy, and survival in middle aged and older individuals.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Clare TazzeoAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden.ORCID 0000-0002-1349-0024
Debora RizzutoAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden.ORCID 0000-0001-6199-9629
Amaia Calderón-LarrañagaAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden.
Serhiy DekhtyarAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden.ORCID 0000-0002-3062-4848
Alberto ZucchelliAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden.
Xin XiaAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden.
Laura FratiglioniAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden.
Davide Liborio VetranoAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden.ORCID 0000-0002-3099-4830

Funding

Swedish Ministry of Health and Social AffairsSwedish Research Council 2017-06088Swedish Research Council for Health, Working Life and Welfare 2016-07175
6 · The paper itself

Abstract

backgroundThis study aims to examine temporal trends in frailty state transitions, and years spent frail, in older Swedish adults.

methodsWe followed the Swedish National Study on Aging and Care in Kungsholmen participants from baseline (2001-2004) for 15 (median: 9.6) years. A 40-deficit frailty index (FI) was constructed to identify 3 frailty states: robust (FI ≤ 0.125), mild frailty (0.125 < FI ≤ 0.25), and moderate and severe frailty (FI  > 0.25). Multistate survival analyses were implemented to obtain hazard ratios (HRs) for frailty state transitions, with birth year and sex as predictors. To examine temporal trends, frailty state-specific life expectancies at age 60 were forecasted for robust persons born in different years (1900, 1910, 1920, 1930, and 1940), also by sex.

resultsAt baseline, the 2 941 participants' mean age was 75 years and 65% were women. Predicted life expectancy and time spent frail from age 60 followed an increasing trend by birth year. Hazards of transitioning from mild frailty to death (HR: 0.89; 95% confidence interval [CI]: 0.83-0.97) and moderate and severe frailty to death (HR: 0.98; 95% CI: 0.97-1.00) were lower for those born later. Women were less likely to transition from robust to mild frailty (HR: 0.81; 95% CI: 0.70-0.93), mild frailty to moderate and severe frailty (HR: 0.80; 95% CI: 0.68-0.93), and moderate and severe frailty to death (HR: 0.68; 95% CI: 0.59-0.78), but spent more time frail.

conclusionsOur results point to an expansion of time spent frail among older Swedish adults over time.

Indexed as

FrailtyAgedAgingFemaleFrail ElderlyGeriatric AssessmentHumansLife ExpectancyMaleSwedenHealth trendsLongitudinal population-based studyMorbidity

Identifiers

PMID37725986
PMCPMC10733192

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.