Evidence map›Paper›PMID 37725675›Full record

ArticleCirculation. Cardiovascular interventions2023

Adoption and Diffusion of Transcarotid Artery Revascularization in Contemporary Practice.

Jesse A Columbo, David H Stone, Pablo Martinez-Camblor, Philip P Goodney, A James O'Malley

Open access · greenAbstract read
In one paragraph

Article in Circulation. Cardiovascular interventions, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. CREST-2 findings are unchanged using an aggregated control group for the CAS and CEA trial.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2026
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  20. Decision aids for patients with carotid stenosis.Journal of vascular surgery · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jesse A ColumboSection of Vascular Surgery, Heart and Vascular Center (J.A.C., D.H.S., P.P.G.), Dartmouth-Hitchcock Medical Center, Lebanon, NH.ORCID 0000-0003-3225-4403
David H StoneSection of Vascular Surgery, Heart and Vascular Center (J.A.C., D.H.S., P.P.G.), Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Pablo Martinez-CamblorDepartment of Anesthesia (P.M.-C.), Dartmouth-Hitchcock Medical Center, Lebanon, NH.ORCID 0000-0001-7845-3905
Philip P GoodneySection of Vascular Surgery, Heart and Vascular Center (J.A.C., D.H.S., P.P.G.), Dartmouth-Hitchcock Medical Center, Lebanon, NH.ORCID 0000-0002-3973-3506
A James O'MalleyGeisel School of Medicine at Dartmouth College, Hanover, NH (J.A.C., D.H.S., P.P.G., A.J.O.).ORCID 0000-0002-5553-8874
Dartmouth College · US

Funding

Comparative-Effectiveness of Procedures for Carotid RevascularizationK08HL165087 · NHLBI · DARTMOUTH-HITCHCOCK CLINIC · PI Jesse A Columbo · 2023 to 2026
$587k
NHLBI NIH HHS K08 HL165087
6 · The paper itself

Abstract

backgroundIn 2015, the FDA approved transcarotid artery revascularization (TCAR) as an alternative to carotid endarterectomy (CEA) and transfemoral carotid artery stenting (TF-CAS) for high-risk patients with carotid stenosis. This was granted in the absence of level 1 evidence to support TCAR. We aimed to document trends in TCAR utilization, its diffusion over time, and the clinical phenotypes of patients undergoing TCAR, CEA, and TF-CAS.

methodsWe used the Vascular Quality Initiative to study patients who underwent TCAR. We calculated the number of TCARs performed and the percent of TCAR utilization versus CEA/TF-CAS. Using data from before TCAR was widespread, we calculated propensity scores for patients to receive CEA. We applied this model to patients undergoing carotid revascularization from 2016 to 2022 and grouped patients by the procedure they ultimately underwent, examining overlap in score distribution to measure patient similarity. We measured the trend of in-hospital stroke/death after TCAR.

resultsWe studied 31 447 patients who underwent TCAR from January 1, 2016 to March 31, 2022. The number of centers performing TCAR increased from 29 to 606. In 2021, TCAR represented 22.5% of carotid revascularizations at centers offering all 3 procedures. The percentage of patients that underwent TCAR who met approved high-risk criteria decreased from 88.5% to 80.9% (

conclusionsTCAR now represents nearly 1-in-4 procedures at centers offering it. TCAR was increasingly performed among standard-risk patients and as a first-line procedural option after stroke. The absence of level 1 evidence underscores the importance of high-quality registry-based analyses to document TCAR's real-world outcomes and durability.

Indexed as

Carotid StenosisStrokeArteriesHumansStentsTreatment Outcomeendarterectomyphenotypepropensity scorerisk factorstent

Identifiers

PMID37725675
PMCPMC10516509
OpenAlexW4386865755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.