Evidence map›Paper›PMID 37725410›Full record

ArticleJournal of medical Internet research2023

Automating Detection of Drug-Related Harms on Social Media: Machine Learning Framework.

Andrew Fisher, Matthew Maclaren Young, Doris Payer, Karen Pacheco, Chad Dubeau, Vijay Mago

Abstract read
In one paragraph

Article in Journal of medical Internet research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Pharmacovigilance in the digital age: gaining insight from social media data.Experimental biology and medicine (Maywood, N.J.) · 2025
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrew FisherDepartment of Mathematics and Computing Science, Saint Mary's University, Halifax, NS, Canada.ORCID 0000-0002-4697-1529
Matthew Maclaren YoungCanadian Centre on Substance Use and Addiction, Ottawa, ON, Canada.ORCID 0000-0001-6125-4678
Doris PayerCanadian Centre on Substance Use and Addiction, Ottawa, ON, Canada.ORCID 0000-0001-9313-2587
Karen PachecoCanadian Medical Protective Association, Ottawa, ON, Canada.ORCID 0000-0001-6180-5601
Chad DubeauCanadian Centre on Substance Use and Addiction, Ottawa, ON, Canada.ORCID 0009-0005-9840-4808
Vijay MagoFaculty of Health, York University, Toronto, ON, Canada.ORCID 0000-0002-9741-3463

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA hallmark of unregulated drug markets is their unpredictability and constant evolution with newly introduced substances. People who use drugs and the public health workforce are often unaware of the appearance of new drugs on the unregulated market and their type, safe dosage, and potential adverse effects. This increases risks to people who use drugs, including the risk of unknown consumption and unintentional drug poisoning. Early warning systems (EWSs) can help monitor the landscape of emerging drugs in a given community by collecting and tracking up-to-date information and determining trends. However, there are currently few ways to systematically monitor the appearance and harms of new drugs on the unregulated market in Canada.

objectiveThe goal of this work is to examine how artificial intelligence can assist in identifying patterns of drug-related risks and harms, by monitoring the social media activity of public health and law enforcement groups. This information is beneficial in the form of an EWS as it can be used to identify new and emerging drug trends in various communities.

methodsTo collect data for this study, 145 relevant Twitter accounts throughout Quebec (n=33), Ontario (n=78), and British Columbia (n=34) were manually identified. Tweets posted between August 23 and December 21, 2021, were collected via the application programming interface developed by Twitter for a total of 40,393 tweets. Next, subject matter experts (1) developed keyword filters that reduced the data set to 3746 tweets and (2) manually identified relevant tweets for monitoring and early warning efforts for a total of 464 tweets. Using this information, a zero-shot classifier was applied to tweets from step 1 with a set of keep (drug arrest, drug discovery, and drug report) and not-keep (drug addiction support, public safety report, and others) labels to see how accurately it could extract the tweets identified in step 2.

resultsWhen looking at the accuracy in identifying relevant posts, the system extracted a total of 584 tweets and had an overlap of 392 out of 477 (specificity of ~84.5%) with the subject matter experts. Conversely, the system identified a total of 3162 irrelevant tweets and had an overlap of 3090 (sensitivity of ~94.1%) with the subject matter experts.

conclusionsThis study demonstrates the benefits of using artificial intelligence to assist in finding relevant tweets for an EWS. The results showed that it can be quite accurate in filtering out irrelevant information, which greatly reduces the amount of manual work required. Although the accuracy in retaining relevant information was observed to be lower, an analysis showed that the label definitions can impact the results significantly and would therefore be suitable for future work to refine. Nonetheless, the performance is promising and demonstrates the usefulness of artificial intelligence in this domain.

Indexed as

Drug-Related Side Effects and Adverse ReactionsSocial MediaArtificial IntelligenceBritish ColumbiaHumansMachine LearningaddictionCanadacommunitydevelopmentdosagedrugearly warning systemFleisslaw enforcementmachine learningmonitoringnew psychoactive substancespharmacologypoisoningpublic healthpublic safetysocial mediatweettweet annotationsTwitter

Identifiers

PMID37725410
PMCPMC10548323

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.