Evidence map›Paper›PMID 37725295›Full record

ArticleBiogerontology2024

Heat-induced hormesis in longevity is linked to heat-stress sensitivity across laboratory populations from diverse altitude of origin in Drosophila buzzatii.

Mariano Almirón, Federico H Gomez, Pablo Sambucetti, Fabian M Norry

Abstract read
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In one paragraph

Article in Biogerontology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mariano AlmirónInstituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA)-CONICET, Universidad de Buenos Aires, C-1428-EHA, Buenos Aires, Argentina.
Federico H GomezInstituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA)-CONICET, Universidad de Buenos Aires, C-1428-EHA, Buenos Aires, Argentina.
Pablo SambucettiInstituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA)-CONICET, Universidad de Buenos Aires, C-1428-EHA, Buenos Aires, Argentina.
Fabian M NorryInstituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA)-CONICET, Universidad de Buenos Aires, C-1428-EHA, Buenos Aires, Argentina. fnorry@ege.fcen.uba.ar.
University of Buenos Aires · ARConsejo Nacional de Investigaciones Científicas y Técnicas · ARFundación Ciencias Exactas y Naturales · AR

Funding

National agency of scientific and technical promotion, Argentina PICT-2017-1426National council of scientific and technical research PIP 2021 GI 11220200100862COUnivertity of Buenos Aires UBACyT 20020170100180BA
6 · The paper itself

Abstract

Heat-induced hormesis in longevity is the increase in life span resulting from the previous exposure to a mild heat stress early in life. Here we examined heat-induced hormesis of Drosophila buzzatii in five mass-mating populations, which were derived from five wild populations along an elevation gradient from 202 to 1855 m above sea level in North-Western Argentina. Five day old flies were exposed to 37.5 °C for 90 min to induce hormesis and its possible variation across altitudinal populations. This heat treatment strongly extended longevity in lowland-derived flies from the most heat-resistant population only. Both heat-induced effects on longevity and heat-knockdown time (heat-stress sensitivity) were negatively correlated to altitude of population of origin. Hormesis was positively correlated to heat-knockdown time across populations. These results indicate that variation in heat-induced hormesis can not be considered as independent of heat-stress sensitivity (or heat-knockdown time) in populations of insects.

Indexed as

DrosophilaLongevityAltitudeAnimalsDrosophila melanogasterHeat-Shock ResponseHormesisAltitudinal clineHeat susceptibilityLife spanLongevity hormesisThermotolerance

Identifiers

PMID37725295
OpenAlexW4386847016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.