Evidence map›Paper›PMID 37725284›Full record

ArticleMolecular biology reports2023

In vitro naive CD4

Zohreh Bolandi, Seyed Mahmoud Hashemi, Mozhgan Abasi, Maryam Musavi, Shahin Aghamiri, Nastaran Miyanmahaleh, Hossein Ghanbarian

Abstract read
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In one paragraph

Article in Molecular biology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zohreh BolandiCellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyed Mahmoud HashemiDepartment of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. smmhashemi@sbmu.ac.ir.
Mozhgan AbasiImmunogenetics Research Center, Department of Tissue Engineering and Applied Cell Sciences, Faculty of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran.ORCID http://orcid.org/0000-0001-6669-4824
Maryam MusaviHealthy Ageing Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Shahin AghamiriDepartment of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nastaran MiyanmahalehDepartment of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hossein GhanbarianCellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. hghanbarian@sbmu.ac.ir.
Shahid Beheshti University of Medical Sciences · IRMazandaran University of Medical Sciences · IRUniversity of Neyshabur · IR

Funding

Shahid Beheshti University of Medical Sciences 6604
6 · The paper itself

Abstract

backgroundGene regulation by microRNA (miRNA) is central in T lymphocytes differentiation processes. Here, we investigate miRNA-29b (miR-29b) roles in the reprogramming of T cell differentiation, which can be a promising therapeutic avenue for various types of inflammatory disorders such as rheumatoid arthritis and multiple sclerosis. METHODS AND

resultsAdipose Mesenchymal Stem Cell-derived exosomes (AMSC-Exo) enriched with miR-29b were delivered into naive CD4

conclusionsIn conclusion, AMSC-Exo-based delivery of miR-29b can be considered as a new fascinating avenue for T cell differentiation inhibition and the future treatment of several inflammatory disorders.

Indexed as

ExosomesMesenchymal Stem CellsMicroRNAsCell DifferentiationT-Lymphocytes, RegulatoryMicroRNAsExosomesMesenchymal stem cellsmiR-29bNaive CD4+ T cellsT cell differentiation

Identifiers

PMID37725284
OpenAlexW4386860207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.