SynthesisInternational journal of colorectal disease2023
Diverticulosis and cardiometabolic risk factors: a systematic literature review.
Synthesis in International journal of colorectal disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Ethnic Disparities in Colonic Diverticulosis Between Arab and Jewish Patients: A Large Nationwide Cohort Study.Journal of immigrant and minority health · 2026Article
- Association betweenBMJ open gastroenterology · 2026Observational
- Association between diabetes mellitus and diverticulosis: a cross-sectional analysis.Wiener klinische Wochenschrift · 2026Article
- Proton pump inhibitor use is not independently associated with colonic diverticulosis in an asymptomatic screening population.Scientific reports · 2026Observational
- Association between Diverticulosis and Colorectal Neoplasia: Analysis from a Large Austrian Database.Journal of clinical medicine · 2024Article
- Association between Cardiovascular Risk Assessment by SCORE2 and Diverticulosis: A Cross-Sectional Analysis.Journal of personalized medicine · 2024Article
- The Impact of Educational Status on the Occurrence of Colonic Diverticula: Insights from an Austrian Cohort Study.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a hypothesis of an association between diverticulosis and metabolic syndrome (MS) or its components, but data on this topic are inconsistent, and a systematic review has not been performed. We conducted a systematic review to investigate the possible association between cardiometabolic risk factors and diverticulosis.
methodsA systematic literature search was conducted via PubMed, Cochrane Library, and Web of Science in December 2022 to collect the necessary data. Studies that examined the association between MS or individual metabolic factors and asymptomatic diverticulosis were included in the review.
resultsOf the potentially relevant articles identified via PubMed (477), Cochrane Library (224), and Web of Science (296), 29 articles met the inclusion criteria and were used for this work. These studies were assessed for study quality using GRADE. Overall, 6 studies were rated as "very low," 19 studies as "low," and 4 studies as "moderate." The data suggest an association between arterial hypertension, obesity, and fatty liver disease in younger patients and diverticulosis. Patient age appears to play an important role in diverticular formation. Data on diabetes mellitus is inconclusive and may require further investigation depending on the location of the diverticula.
conclusionBased on the synthesized data, there is an association between arterial hypertension, obesity, and fatty liver disease in younger patients. The formation of diverticula seems to be influenced by age and genetic factors. The study suggests a connection with cardiometabolic risk factors. To gain a better understanding of the role of metabolic risk factors in asymptomatic diverticulosis, targeted studies are necessary based on these findings.
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