Evidence map›Paper›PMID 37725150›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2023

Use and safety of peripherally inserted central catheters and midline catheters in palliative care cancer patients: a retrospective review.

Eva Gravdahl, Siri Steine, Knut Magne Augestad, Olav Magnus Fredheim

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06770374 (Effectiveness of a Zinc Oxide Adhesive Securement Device in the Fixation of Midline and Peripherally Inserted Central Catheters in Hospitalized Adult Patients), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06770374 narecruitingnot on this mapstarted 2025, after this paper: background citation

Effectiveness of a Zinc Oxide Adhesive Securement Device in the Fixation of Midline and Peripherally Inserted Central Catheters in Hospitalized Adult Patients: Randomised Clinical Trial

TypeinterventionalSponsorHospital Arnau de VilanovaRan2025 to 2026Enrolled400ConditionsVascular Access Complication, Skin and Subcutaneous Tissue Disorders, Phlebitis, PainArmsControl group: acrylic adhesive sutureless fixation device, Intervention Group: zinc oxide sutureless fixation device, PICC, Midline, Ultrasound scanner
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eva GravdahlDepartment of Palliative Medicine, Akershus University Hospital, Sykehusveien 25, 1478, Lørenskog, Norway. eva.gravdahl@ahus.no.
Siri SteineDepartment of Palliative Medicine, Akershus University Hospital, Sykehusveien 25, 1478, Lørenskog, Norway.
Knut Magne AugestadInstitute of Clinical Medicine, University of Oslo, Problemveien 7, 0315, Oslo, Norway.
Olav Magnus FredheimDepartment of Palliative Medicine, Akershus University Hospital, Sykehusveien 25, 1478, Lørenskog, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSome cancer patients in palliative care require intravenous administration of symptom relieving drugs. Peripherally inserted central catheters (PICCs) and midline catheters (MCs) provide easy and accessible intravenous access. However, limited evidence supports the use of these devices in palliative care. The aim was to assess the use, safety, and efficacy of PICC and MC in this patient population.

methodsA retrospective study of all palliative care cancer patients who received PICC or MC at the Department of Palliative Medicine at Akershus University Hospital between 2020 and 2022.

resultsA total of 374 patients were included; 239 patients received a PICC and 135 an MC with a total catheterization duration of 11,698 days. The catheters remained in place until death in 91% of patients, with a median catheter dwell time of 21 days for PICCs and 2 days for MCs. The complication rate was 3.3 per 1000 catheter days, with minor bleeding and accidental dislocation as the most common. The catheters were utilized primarily for opioids and other symptom directed treatments, and 89% of patients received a patient or nurse-controlled analgesia pump. Patients with PICC or MC discharged to home or nursing homes spent 81% of their time out of hospital.

conclusionPICC and MC provide safe parenteral access for palliative care cancer patients where intravenous symptom treatment is indicated. Their use can facilitate intravenous symptom treatment beyond the confines of a hospital and supplement the traditional practice relying on subcutaneous administration.

Indexed as

NeoplasmsPalliative CareCathetersHospitals, UniversityHumansPain ManagementRetrospective StudiesCancerDrug administrationIntravenous accessMidline catheterPalliative carePeripherally inserted central catheter

Identifiers

PMID37725150
PMCPMC10509059

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.