Evidence map›Paper›PMID 37724617›Full record

ArticleCancer medicine2023

Ten-year work burden after prostate cancer treatment.

Samuel L Washington, Peter E Lonergan, Janet E Cowan, Shoujun Zhao, Jeanette M Broering, Nynikka R Palmer, Cameron Hicks, Matthew R Cooperberg, Peter R Carroll

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samuel L WashingtonDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA.ORCID 0000-0002-2467-6115
Peter E LonerganDepartment of Urology, St. James's Hospital, Dublin, Ireland.ORCID 0000-0001-7233-8156
Janet E CowanDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA.
Shoujun ZhaoDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA.
Jeanette M BroeringDepartment of Surgery, University of California, San Francisco, California, USA.
Nynikka R PalmerDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA.
Cameron HicksDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA.
Matthew R CooperbergDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA.
Peter R CarrollDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA.

Funding

UCSF Goldberg-Benioff Program in Translational Cancer Biology
6 · The paper itself

Abstract

introductionWe aim to characterize the magnitude of the work burden (weeks off from work) associated with prostate cancer (PCa) treatment over a 10-year period after PCa diagnosis and identify those at greatest risk. MATERIALS AND

methodsWe identified men diagnosed with PCa treated with radical prostatectomy, radiation therapy, or active surveillance/watchful waiting within CaPSURE. Patients self-reported work burden and SF36 general health scores via surveys before and 1,3,5, and 10 years after treatment. Using multivariate repeated measures generalized estimating equation modeling we examined the association between primary treatment with risk of any work weeks lost due to care.

resultsIn total, 6693 men were included. The majority were White (81%, 5% Black, and 14% Other) with CAPRA low- (60%) or intermediate-risk (32%) disease and underwent surgery (62%) compared to 29% radiation and 9% active surveillance. Compared to other treatments, surgical patients were more likely to report greater than 7 days off work in the first year, with relatively less time off over time. Black men (RR 0.64, 95% CI 0.54-0.77) and those undergoing radiation (vs. surgery, RR 0.46, 95% CI 0.41-0.51) were less likely to report time off from work over time. Mean baseline GH score (73 [SD 18]) was similar between race and treatment groups, and stable over time.

conclusionsThe work burden of cancer care continued up to 10 years after treatment and varied across racial groups and primary treatment groups, highlighting the multifactorial nature of this issue and the call to leverage greater resources for those at greatest risk.

Indexed as

Cost of IllnessProstatic NeoplasmsAgedHumansMaleMiddle AgedProstatectomyWatchful Waitingdisease managementprostate cancerracial groupswork burden

Identifiers

PMID37724617
PMCPMC10557888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.