Evidence map›Paper›PMID 37724554›Full record

ArticleRenal failure2023

A high platelet-to-lymphocyte ratio predicts all-cause mortality and cardiovascular mortality in maintenance hemodialysis patients.

Yanping Zhang, Aihong Zhang, Lin Wei, Kaiming Ren, Qian Wang, Bing Shao, Chen Zhao, Zhuo Ren, Jiuxu Bai, Ning Cao

Abstract read
In one paragraph

Article in Renal failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yanping ZhangDepartment of Blood Purification, General Hospital of Northern Theatre Command, Shenyang, Liaoning, China.
Aihong ZhangDepartment of Blood Purification, General Hospital of Northern Theatre Command, Shenyang, Liaoning, China.
Lin WeiDepartment of Blood Purification, General Hospital of Northern Theatre Command, Shenyang, Liaoning, China.
Kaiming RenDepartment of Blood Purification, General Hospital of Northern Theatre Command, Shenyang, Liaoning, China.
Qian WangDepartment of Blood Purification, General Hospital of Northern Theatre Command, Shenyang, Liaoning, China.
Bing ShaoDepartment of Blood Purification, General Hospital of Northern Theatre Command, Shenyang, Liaoning, China.
Chen ZhaoDepartment of Blood Purification, General Hospital of Northern Theatre Command, Shenyang, Liaoning, China.
Zhuo RenDepartment of Blood Purification, General Hospital of Northern Theatre Command, Shenyang, Liaoning, China.
Jiuxu BaiDepartment of Blood Purification, General Hospital of Northern Theatre Command, Shenyang, Liaoning, China.
Ning CaoDepartment of Blood Purification, General Hospital of Northern Theatre Command, Shenyang, Liaoning, China.ORCID 0000-0001-5114-028X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to further assess whether the platelet-to-lymphocyte ratio (PLR) is independently associated with all-cause mortality and cardiovascular mortality in maintenance hemodialysis (MHD) patients.

methodsFrom January 1, 2014, to December 31, 2014, patients undergoing regular hemodialysis in the Blood Purification Center of the General Hospital of Northern Theatre Command were retrospectively selected. A total of 303 MHD patients were enrolled in accordance with the inclusion and exclusion criteria. For each patient, the endpoint of follow-up was either death or December 31, 2021. The primary endpoints were all-cause and cardiovascular death. A receiver operating characteristic (ROC) curve was drawn to detect the predictive ability of PLR, and the optimal critical value of PLR was determined to be 107.57. Kaplan-Meier curves and Cox proportional analysis were used to assess the prognostic value of PLR. We used the same method to evaluate the correlation between the neutrophil-to-lymphocyte ratio (NLR) and the prognosis of MHD patients.

resultsAt the end of follow-up, 128 MHD patients had progressed to all-cause death, and 73 MHD patients had progressed to cardiovascular death. In multivariate Cox regression, both the high PLR group and the high NLR group were independently associated with all-cause mortality (HR 2.608, 95% CI 1.579-4.306,

conclusionsHigh PLR levels can independently predict all-cause and cardiovascular mortality in MHD patients.

Indexed as

Cardiovascular DiseasesCardiovascular SystemHumansLymphocytesRenal DialysisRetrospective Studiesall-cause mortalitycardiovascular mortalitymaintenance hemodialysisneutrophil-to-lymphocyte ratioPlatelet-to-lymphocyte ratio

Identifiers

PMID37724554
PMCPMC10512768

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.