ArticleJournal of cachexia, sarcopenia and muscle2023
Effects of sarcopenia and frailty on postoperative recovery in elderly patients: A prospective cohort study.
Article in Journal of cachexia, sarcopenia and muscle, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Mapping the global landscape of behavioral interventions for sarcopenia in older adults: implications for clinical practice and research prioritization.BMC geriatrics · 2026Pooled it
- Sarcopenia, frailty syndrome and obstructive sleep apnea as elements of the aging phenotype in head and neck cancer and upper airway disorders: a scoping review.Frontiers in medicine · 2026Pooled it
- Frailty as a predictor of postoperative outcomes in older gastroesophageal cancer patients: a systematic review and meta-analysis.BMC geriatrics · 2025Pooled it
- Early postoperative hypophosphatemia is an independent predictor of ileus after transforaminal lumbar interbody fusion: a multicenter retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Association of Combined Nutritional Risk and Oral Frailty Assessment with Postoperative Complications in Older Surgical Patients: A Pilot Cohort Study.JMA journal · 2026Article
- Outcomes of living donor liver transplantation in elderly Egyptian patients: a retrospective study.Langenbeck's archives of surgery · 2026Article
- Frailty and sarcopenia proxies are associated with postoperative outcomes after abdominal wall reconstruction: a national database analysis.Surgical endoscopy · 2026Article
- The application value of frailty assessment tools in the perioperative period: A narrative review.Journal of anesthesia and translational medicine · 2026Review
- Opportunistic CT-Based Sarcopenia Screening: Masseter Muscle Index as a Prognostic Indicator of Prolonged Hospitalization in Carotid Endarterectomy.Diagnostics (Basel, Switzerland) · 2026Article
- Skeletal muscle index and hand grip strength as predictors of postoperative recovery in patients with gastrointestinal tumors.BMC gastroenterology · 2026Observational
- The association between sarcopenia and frailty in older adults: a moderated mediation model.BMC geriatrics · 2026Article
- Prognostic utility of sarcopenia and frailty on postoperative complication and mortality in older intermediate risk cancer surgery.BMC geriatrics · 2026Article
- Effects of Pelvic Organ Prolapse Surgery on Physical Function, Muscle Strength, and Skeletal Muscle Mass.International urogynecology journal · 2026Article
- Skeletal Muscle Density as an Independent Predictor of Prolonged Postoperative Hospital Stay After Surgery for Acute Cholecystitis.Journal of clinical medicine · 2026Article
- Sex and Age Differences in Outcomes of Traumatic Brain Injury: Findings from the Japan Neurotrauma Data Bank.Journal of clinical medicine · 2026Article
- Can the frailty score independently predict postoperative morbidity in patients with colorectal cancer? A prospective observational study.BMC geriatrics · 2026Observational
- Association between frailty status and delayed observation-room retention after painless gastrointestinal endoscopy in older patients.Frontiers in medicine · 2026Article
- Development and validation of a machine learning-based sarcopenia prediction model using the triglyceride glucose-frailty index.The Journal of international medical research · 2026Article
- Metabolomic characterization of frailty identifies subtype-specific management strategies.NPJ digital medicine · 2025Article
- Sarcopenia in atrial fibrillation: a risk factor for adverse outcomes in a UK Biobank study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSarcopenia and frailty are both age-related declines in functional reserve that are linked to adverse health outcomes. It is critical to know about the outcomes of a combination of these conditions. The study aimed to investigate the effects of sarcopenia and frailty on postoperative recovery in elderly patients and to explore risk factors.
methodsThis prospective cohort study was conducted among 608 patients aged ≥60 years, American Society of Anesthesiologists I-III, who were scheduled to undergo thoracic (non-cardiac) and abdominal surgery from 1 March 2022 to 31 October 2022 at the Affiliated Hospital of Xuzhou Medical University. Frailty was measured by the 28-item frailty index, and sarcopenia was assessed sarcopenia was assessed by skeletal muscle index in computed tomographic scan, handgrip strength and 6-m walk. Participants were classified as follows: Group A: both sarcopenia and frailty; Group B: sarcopenia only; Group C: frailty only; and Group D: neither frailty nor sarcopenia. The primary outcome was 90-day morbidity. Multivariable logistic regression model was used to estimate the association between sarcopenia, frailty and 90-day morbidity.
resultsThe median (interquartile range) age of participants was 68 (64-72) years, and 62.7% were men. The prevalence rates of sarcopenia and frailty were 32.8% and 47.6%, respectively. The 90-day morbidity in Group A was 58.5%, in Group B was 46.2%, in Group C was 42.0% and in Group D was 28.8%, and the difference was significant (P < 0.001). In the multivariable analysis, both sarcopenia and frailty [odds ratio (OR), 2.21; 95% confidence interval (CI), 1.26-3.89], sarcopenia only (OR, 1.84; 95% CI, 1.01-3.36), frailty only (OR, 1.77; 95% CI, 1.03-3.03), women (OR, 0.67; 95% CI, 0.45-0.99), body mass index (OR, 0.94; 95% CI, 0.88-0.99), pre-operative albumin (OR, 0.96; 95% CI, 0.91-1.00) and operative stress score (OSS) [OSS 3 (OR, 2.09; 95% CI, 1.21-3.67); OSS 4-5 (OR, 3.81; 95% CI, 2.31-6.42)] were independently associated with 90-day morbidity. In the multivariable analysis with inverse probability weighting adjusted cohort, sarcopenia and frailty were also significantly associated with 90-day morbidity.
conclusionsSarcopenia and frailty were associated with higher risks of postoperative 90-day morbidity in elderly patients alone and in combination. Sex, body mass index, pre-operative albumin and operative stress were also independent factors for postoperative morbidity within 90 days.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.