Evidence map›Paper›PMID 37724397›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2023

Mechanism of

Quan Zhu, Baisheng Huang, Lixiang Wu, Qizhi Luo

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 71% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Quan ZhuDepartment of Immunology, School of Basic Medicine, Central South University, Changsha 410008. 243790933@qq.com.
Baisheng HuangDepartment of Physiology, School of Basic Medicine, Central South University, Changsha 410008, China.
Lixiang WuDepartment of Physiology, School of Basic Medicine, Central South University, Changsha 410008, China.
Qizhi LuoDepartment of Immunology, School of Basic Medicine, Central South University, Changsha 410008. luoqz1025@163.com.
Central South University · CN

Funding

the Changsha Guiding Science and Technology Project kzd22002the Natural Science Foundation of Hunan Province 2019JJ40398 and 2020JJ4768
6 · The paper itself

Abstract

objectivesPaired box gene 6 (

methodsThe protein levels of PAX6, soluble major histocompatibility complex class I-like protein A (sMICA) and soluble UL16 binding protein 2 (sULBP2) in peripheral blood from 68 cases of hepatocellular carcinoma (HCC) patients and 10 healthy volunteers were detected by ELISA. Hepatocellular carcinoma cell line (HepG2, LM3) and human normal liver cells (LO2) were cultured at 37 ℃ and 5% CO

resultsCompared with the healthy volunteers, the expressions of PAX6 in the HCC patients were significantly decreased (

conclusionsThe expression of PAX6 is decreased in serum of HCC patients and hepatocellular carcinoma cell lines. Overexpression of

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsCell LineFemaleHumansKiller Cells, NaturalMatrix Metalloproteinase 2Matrix Metalloproteinase 9PAX6 Transcription FactorPregnancyMatrix Metalloproteinase 2Matrix Metalloproteinase 9PAX6 protein, humanPAX6 Transcription Factorcell growthhepatocellular carcinomametalloproteinasenatural killer cellspaired box gene 6

Identifiers

PMID37724397
PMCPMC10930045
OpenAlexW4386843564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.