ArticleJournal of inflammation research2023
An Easy-to-Use Nomogram Based on SII and SIRI to Predict in-Hospital Mortality Risk in Elderly Patients with Acute Myocardial Infarction.
Article in Journal of inflammation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic value of systemic inflammation response index in patients with myocardial infarction: a systematic review and meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Effect of Clopidogrel on Early Inflammatory Response and In-Hospital Outcomes in Patients with Myocardial Infarction.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Predicting In-Hospital Mortality in Acute Mesenteric Ischemia: The RADIAL Score.Journal of clinical medicine · 2026Article
- FT3 Levels and Systemic Inflammation: Evidence From a Population-Based NHANES Analysis.Mediators of inflammation · 2026Article
- Association between the systemic immune-inflammation index and mortality risk in myocardial infarction patients: a retrospective cohort study.European journal of medical research · 2025Article
- Joint association of estimated glucose disposal rate and systemic inflammation response index with all-cause and cardiovascular mortality in patients with dyslipidemia: a nationwide prospective cohort study.Diabetology & metabolic syndrome · 2025Article
- Systemic Immune-Inflammation Index and Related Hematologic Markers as Prognostic Tools in Type 2 Diabetes.Medicina (Kaunas, Lithuania) · 2025Article
- Development and validation of an LDH-focused nomogram for the early prediction of heart failure in patients with acute ST-elevation myocardial infarction after percutaneous coronary intervention.Lipids in health and disease · 2025Article
- Association between novel inflammatory biomarkers SII, SIRI, and obesity in sedentary adults: NHANES 2007-2020.Scientific reports · 2025Article
- Development of peripheral biomarker-based prognostic nomograms for short-term and long-term survival in immune checkpoint inhibitor-associated myocarditis.Cardiovascular diagnosis and therapy · 2025Article
- The Complex Inflammatory and Nutritional Indices to Predict Prognostic Risk for Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.Immunity, inflammation and disease · 2025Article
- Association of the systemic immune-inflammation index with clinical outcomes in acute myocardial infarction patients with hypertension.BMC immunology · 2025Article
- Associations of Inflammatory Markers With Neurological Dysfunction and Prognosis in Patients With Progressive Stroke.European journal of neurology · 2025Article
- Prognostic implications of system inflammation response index in atrial fibrillation patients with type 2 diabetes mellitus.Scientific reports · 2025Article
- Prognostic value of inflammatory markers for all-cause mortality in patients with acute myocardial infarction in the coronary care unit: a retrospective study based on MIMIC-IV database.Frontiers in cardiovascular medicine · 2025Article
- The Systemic Inflammation Response Index as an Independent Predictor of Acute Kidney Injury in Critically Ill Patients With Acute Myocardial Infarction: Insights From a Large-Scale Cohort Study.Mediators of inflammation · 2025Article
- Predicting In-Hospital Mortality in Myocardial Infarction: A Nomogram-Based Retrospective Analysis of the MIMIC-IV Database.Vascular health and risk management · 2025Article
- The mediating role of insulin resistance in the association between inflammatory score and MAFLD: NHANES 2017-2018.Immunity, inflammation and disease · 2024Article
- The association between triglyceride-glucose index and its combination with systemic inflammation indicators and all-cause and cardiovascular mortality in the general US population: NHANES 1999-2018.Lipids in health and disease · 2024Article
- Screening significance of systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) in coronary heart disease of symptomatic youth.Immunity, inflammation and disease · 2024Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: Inflammatory response is closely associated with poor prognosis in elderly patients with acute myocardial infarction (AMI). The aim of this study was to develop an easy-to-use predictive model based on medical history data at admission, systemic immune inflammatory index (SII), and systemic inflammatory response index (SIRI) to predict the risk of in-hospital mortality in elderly patients with AMI. Methods: We enrolled 1550 elderly AMI patients (aged ≥60 years) with complete medical history data and randomized them 5:5 to the training and validation cohorts. Univariate and multivariate logistic regression analyses were used to screen risk factors associated with outcome events (in-hospital death) and to establish a nomogram. The discrimination, calibration, and clinical application value of nomogram were evaluated based on receiver operating characteristic (ROC) curve, calibration curve, and decision curve analysis (DCA), respectively. Results: The results of multivariate logistic regression showed that age, body mass index (BMI), previous stroke, diabetes, SII, and SIRI were associated with in-hospital death, and these indicators will be included in the final prediction model, which can be obtained by asking the patient's medical history and blood routine examination in the early stage of admission and can improve the utilization rate of the prediction model. The areas under the ROC curve for the training and validation cohorts nomogram were 0.824 (95% CI 0.796 to 0.851) and 0.809 (95% CI 0.780 to 0.836), respectively. Calibration curves and DCA showed that nomogram could better predict the risk of in-hospital mortality in elderly patients with AMI. Conclusion: The nomogram constructed by combining SII, SIRI, and partial medical history data (age, BMI, previous stroke, and diabetes) at admission has a good predictive effect on the risk of in-hospital death in elderly patients with AMI.
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